CLK1 and RBM39

Number of citations of the paper that reports this interaction (PubMedID 26167880)
16

Data Source:
BioGRID (enzymatic study)

		CLK1	RBM39
Description		CDC like kinase 1	RNA binding motif protein 39
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm	Nucleoplasm Microtubule Cytoskeleton Nuclear Speck Protein-containing Complex Centriolar Satellite
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Non-membrane Spanning Protein Tyrosine Kinase Activity Protein Binding ATP Binding	RNA Binding Protein Binding
	Biological Process	Peptidyl-serine Phosphorylation Peptidyl-threonine Phosphorylation Peptidyl-tyrosine Phosphorylation Regulation Of RNA Splicing Protein Autophosphorylation	RNA Processing MRNA Processing RNA Splicing
Pathways
Drugs		Debromohymenialdisine ethyl 3-[(E)-2-amino-1-cyanoethenyl]-6,7-dichloro-1-methyl-1H-indole-2-carboxylate
Diseases
GWAS		Breast cancer ( 27117709) Breast cancer (estrogen-receptor negative) ( 27117709) Triptolide cytotoxicity ( 26121980)	Blood protein levels ( 28240269)
Interacting Genes		159 interacting genes: ABCA13 ACOX2 ANKFY1 ARHGEF12 ARPC4 ASL ASXL3 ATP10A ATP4A BCLAF1 BCS1L C1orf94 CDCP1 CDH23 CDK12 CELSR3 CENPE CEP95 CFAP20DC CFAP251 CKAP5 CLASRP COCH CRNKL1 CTNND2 CUL3 CWC27 CYP46A1 DBR1 DENND4A DNAJC13 DNAJC24 DPYD DSC2 ECE1 ELP6 ENO1 ERFE FAM160B2 FAM189A1 FAT1 FBF1 GEMIN5 GOLM1 GRM6 GSDMB H2BC12 HADH HIVEP1 HNMT HNRNPA0 HNRNPA1 HNRNPA3 HSP90AB2P HSPBP1 HTATSF1 ICE1 IMPDH2 IP6K1 ITGA5 KATNA1 KHDRBS1 KIF14 KIF23 KRT8 KRTAP10-7 LINS1 LMNA LUC7L3 MAP3K21 MAP7 MBP MFHAS1 MFSD10 MICU3 MKRN2 MTBP MTCL1 MYOM1 NCL NCOR1 NF1 NPM1 NUP153 PATZ1 PDE9A PHF3 PHLDB2 PIAS4 PIP4K2B PKD1L1 PLAAT5 PLXDC2 PPFIBP2 PPHLN1 PPIG PPP1CB PRDX5 PRKDC PRMT5 PRPF38A PRPF4 PRPF4B PTPN1 PTPN22 RAD21L1 RAPH1 RASL12 RBBP6 RBM15 RBM39 RBMX REV1 RLF RPL5 RPS4Y1 RPUSD3 SAFB SAMD9L SCARA3 SERPINI2 SF3B1 SFMBT2 SHROOM1 SLC35D3 SLFN5 SPEN SPTBN4 SRPK1 SRPK2 SRRM1 SRRM2 SRSF1 SRSF3 SRSF5 SRSF6 SRSF7 SSBP3 STIP1 STK31 SVOP TEX11 THRAP3 THY1 TJP2 TLN2 TMPO TMPRSS2 TNIP2 TP53RK TRA2B UBL5 UNC13B VWA7 YTHDC1 YWHAG ZC3H13 ZMYND10 ZNF148	51 interacting genes: AK8 APP ARL6IP4 BANP CHERP CLK1 CLK2 DDX39B ESR1 ESR2 FAM200A GOLGA2 H1-2 HNRNPH2 HOMEZ HSPB1 JUN KHDC4 KRTAP12-2 MCPH1 MLX MTNR1A NCOA6 NKAP NKAPD1 PGR PHC2 PPIG PRPF3 PRPF38A PRPF40A RBM23 RBM25 REL RNF113A RP9P SAP18 SAP30BP SDCBP SF3B4 SP100 SREK1IP1 SRPK1 SRPK2 SRSF11 THAP1 TOE1 TTC14 U2AF2 ZBTB22 ZCCHC10
Entrez ID		1195	9584
HPRD ID		09058	09201
Ensembl ID		ENSG00000013441	ENSG00000131051
Uniprot IDs		P49759	A0A384NQ03 B4DRA0 E1P5S2 Q14498 Q6N037
PDB IDs		1Z57 2VAG 5J1V 5J1W 5X8I 6FT8 6FT9 6FYO 6G33 6I5H 6I5I 6I5K 6I5L 6KHD 6Q8K 6Q8P 6RAA	2JRS 2MHN 4OO6 4OZ0 4OZ1 4YUD 6Q0R 6Q0V 6Q0W
Enriched GO Terms of Interacting Partners?
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