TWIST2 and PLCG2

  • Number of citations of the paper that reports this interaction (PubMedID 25814554)
  • 22
  • Data Source:
  • BioGRID (two hybrid)

TWIST2

PLCG2

Description twist family bHLH transcription factor 2 phospholipase C gamma 2
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease (late onset) ( 28714976)
  • Blood protein levels ( 30072576)
  • Breast cancer (menopausal hormone therapy interaction) ( 24080446)
  • Coronary artery disease ( 29212778)
  • Dental caries (decayed, missing and filled teeth) ( 31533690)
  • Height ( 28552196)
  • Inflammatory bowel disease ( 28067908)
  • Mean platelet volume ( 27863252)
  • Metabolite levels ( 23823483)
  • Platelet distribution width ( 27863252)
  • Ulcerative colitis ( 28067908)
  • Upper eyelid morphology ( 29921221)
  • Venous thromboembolism ( 31420334 31676865)
  • Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes 6 interacting genes: CRK MEF2C PLCG2 SREBF1 TCF12 TCF4 50 interacting genes: ASB9 BLK BLNK BTK CBLB CD19 DAPP1 EGFR ELK1 EPOR EPYC ESD FCER1G FLT1 FYN GAB1 GAB2 GABPB2 HCK HSPD1 IRS1 ISL1 ITK JAK1 JAK2 KCTD17 KDR KHDRBS1 LAT LAT2 LCK LCP2 LHX8 LIME1 LYN NPM1 PRKD1 PTPN6 PTTG1 RALBP1 RTL10 SETD9 SH3BP2 SHC1 SYK TEC TP53 TWIST2 ZKSCAN7 ZNF512B
Entrez ID 117581 5336
HPRD ID 09616 02570
Ensembl ID ENSG00000233608 ENSG00000197943
Uniprot IDs A1MB48 Q8WVJ9 P16885
PDB IDs 2K2J 2W2W 2W2X
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
Tagcloud (Intersection) ?