RLN3 and RXFP1

Number of citations of the paper that reports this interaction (PubMedID 14522968)
56

Data Source:
HPRD (in vivo, in vitro)

		RLN3	RXFP1
Description		relaxin 3	relaxin family peptide receptor 1
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GO Annotations	Cellular Component	Extracellular Region	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	G Protein-coupled Receptor Binding Hormone Activity Protein Binding	G Protein-coupled Receptor Activity Protein Binding G Protein-coupled Peptide Receptor Activity Metal Ion Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway	G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Activation Of Adenylate Cyclase Activity Hormone-mediated Signaling Pathway
Pathways		G alpha (s) signalling events G alpha (i) signalling events Relaxin receptors ADORA2B mediated anti-inflammatory cytokines production	G alpha (s) signalling events Relaxin receptors ADORA2B mediated anti-inflammatory cytokines production
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)	Acute lymphoblastic leukemia (childhood) ( 22076464) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		3 interacting genes: RXFP1 RXFP3 RXFP4	4 interacting genes: RLN1 RLN2 RLN3 SRPK2
Entrez ID		117579	59350
HPRD ID		06031	05975
Ensembl ID		ENSG00000171136	ENSG00000171509
Uniprot IDs		B2RU28 K7ENX1 Q8WXF3	A0A087WWV0 A0A0A0MT52 B3KV27 B4DGP2 Q59H16 Q9HBX9
PDB IDs		2FHW 2K1V	2JM4 2M7P
Enriched GO Terms of Interacting Partners?
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