RAB3IP and RUFY1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		RAB3IP	RUFY1
Description		RAB3A interacting protein	RUN and FYVE domain containing 1
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GO Annotations	Cellular Component	Nucleus Cytosol Cytoskeleton Lamellipodium	Cytoplasm Endosome Cytosol Nuclear Speck Early Endosome Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Rab Guanyl-nucleotide Exchange Factor Activity	Protein Binding Lipid Binding SH3 Domain Binding SH2 Domain Binding Metal Ion Binding
	Biological Process	Protein Targeting To Membrane Ciliary Basal Body-plasma Membrane Docking	Phosphatidylinositol Biosynthetic Process Endocytosis Small GTPase Mediated Signal Transduction Protein Transport Regulation Of Endocytosis
Pathways		Anchoring of the basal body to the plasma membrane VxPx cargo-targeting to cilium BBSome-mediated cargo-targeting to cilium RAB GEFs exchange GTP for GDP on RABs	Synthesis of PIPs at the plasma membrane
Drugs
Diseases
GWAS		Diastolic blood pressure ( 27841878) Height ( 28552196) Logical memory (delayed recall) in normal cognition ( 29274321)	Daytime sleep phenotypes ( 27126917) Dental caries (decayed and filled deciduous teeth) ( 31533690) Eating disorders ( 22911880) Lung cancer ( 28604730)
Interacting Genes		21 interacting genes: BANP CHCHD3 FAM124A KRT40 MVP NAA10 PLOD3 PPL RAB11A RAB3A RAB3D RAB3IL1 RAB8A RAB8B RUFY1 SFN SSX2 SUV39H2 TRAPPC6A TXNDC5 ZNF410	16 interacting genes: AP3B2 AP3D1 AP3M1 AP3S1 BMX EPHA3 GIT2 ITSN2 PIAS2 RAB14 RAB39B RAB3IP RAB4A RAB5A TXNDC17 UTP25
Entrez ID		117177	80230
HPRD ID		10565	15282
Ensembl ID		ENSG00000127328	ENSG00000176783
Uniprot IDs		Q96QF0	A8K7B1 Q96T51
PDB IDs		4LHX 4LHY 4LHZ 4UJ3 4UJ4 4UJ5 6F6P	2YQM 2YW8
Enriched GO Terms of Interacting Partners?
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