SH2D1B and MAPK8IP2

Number of citations of the paper that reports this interaction (PubMedID 25814554)
22

Data Source:
BioGRID (two hybrid)

		SH2D1B	MAPK8IP2
Description		SH2 domain containing 1B	mitogen-activated protein kinase 8 interacting protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol	Cytoplasm Plasma Membrane Postsynaptic Density Protein-containing Complex Neuronal Cell Body
	Molecular Function	Protein Binding Protein Binding, Bridging	Amyloid-beta Binding MAP-kinase Scaffold Activity Structural Molecule Activity Protein Binding Kinesin Binding Protein Kinase Binding Protein-containing Complex Binding
	Biological Process	Adaptive Immune Response Leukocyte Activation Involved In Immune Response Positive Regulation Of Natural Killer Cell Mediated Immunity Innate Immune Response Positive Regulation Of Innate Immune Response Regulation Of Immune Response	Behavioral Fear Response Receptor-mediated Endocytosis Signal Complex Assembly JNK Cascade Mating Behavior Regulation Of Signaling Receptor Activity Positive Regulation Of Stress-activated MAPK Cascade Social Behavior Positive Regulation Of Endocytosis Regulation Of JNK Cascade Nonassociative Learning Dendrite Morphogenesis Regulation Of Synaptic Transmission, Glutamatergic Excitatory Postsynaptic Potential Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of NMDA Receptor Activity Regulation Of AMPA Receptor Activity Negative Regulation Of Apoptotic Signaling Pathway
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS		Takayasu arteritis ( 25604533)	Hip circumference ( 28552196)
Interacting Genes		11 interacting genes: APP CD244 CD84 ERBB2 LY9 MAPK8IP2 PRDX1 PTK2 SLAMF1 STAT4 TRIM54	84 interacting genes: ADRB2 AFG3L2 ANAPC10 APP ASRGL1 BBS10 C1QTNF3 C22orf39 C8orf33 CFL1 CHN1 CRMP1 CRP CTNNBL1 DUSP16 DUSP18 EGFR ERBB2 ERG28 EZH2 FGF12 FGF13 FSCN1 GALNT3 GBP2 HLA-C IGIP ING4 ITSN1 KIFC2 KLC1 LEFTY2 LRP1 LRP2 LRP8 LSM8 MAGED4B MAP2K3 MAP2K7 MAP3K10 MAP3K11 MAP3K12 MAPK10 MAPK8 MAPK8IP1 MAPK8IP3 MAPK9 MASP1 MNDA MRE11 MSRB3 NDUFS6 NUMB PLXNA3 PRSS23 RAI1 RBM4 RBX1 RPS6KB2 RYBP SCLT1 SH2D1B SLC39A13 SLPI SMARCB1 SMS SPINK2 SPSB3 SRP19 SYNE2 TARBP2 TIAM1 TMEM128 TP53BP2 UNC119 USP46 VCP VPS33B VRK2 YY1AP1 ZNF593 ZNF670 ZNF784 ZNRD1
Entrez ID		117157	23542
HPRD ID		12248	09674
Ensembl ID		ENSG00000198574	ENSG00000008735
Uniprot IDs		O14796	Q13387
PDB IDs		5KAZ
Enriched GO Terms of Interacting Partners?
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