PNMA5 and ARPC4

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		PNMA5	ARPC4
Description		PNMA family member 5	actin related protein 2/3 complex subunit 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Nucleus Cytosol Arp2/3 Protein Complex Site Of Double-strand Break Cell Projection Extracellular Exosome
	Molecular Function	Protein Binding Identical Protein Binding	Structural Constituent Of Cytoskeleton Protein Binding Enzyme Binding Protein Binding, Bridging Actin Filament Binding
	Biological Process	Positive Regulation Of Apoptotic Process	Actin Filament Polymerization Arp2/3 Complex-mediated Actin Nucleation Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Actin Nucleation Ephrin Receptor Signaling Pathway Membrane Organization
Pathways			Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation EPHB-mediated forward signaling RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs Clathrin-mediated endocytosis FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs			N-[2-(2-methyl-1H-indol-3-yl)ethyl]thiophene-2-carboxamide (2S)-2-(3-bromophenyl)-3-(5-chloro-2-hydroxyphenyl)-1,3-thiazolidin-4-one
Diseases
GWAS
Interacting Genes		32 interacting genes: AP1M1 ARPC4 C11orf49 CARD9 CCDC102B CCNC CDC23 CEP57L1 CETN2 DDX6 GLIPR2 GORASP2 GRB2 KPNA2 MOAP1 MYO15B NTAQ1 PNMA1 POLR3C PRKAA1 PSMA1 RAD23B SH3KBP1 TBC1D22B TNPO2 TTC23 TXNL4B VIM VPS28 ZBTB25 ZFYVE26 ZMYND19	11 interacting genes: ACTR2 ACTR3 ARPC1B ARPC2 ARPC3 ARPC5 ARPC5L CLK1 NELFCD PNMA5 RNF130
Entrez ID		114824	10093
HPRD ID		06678	10368
Ensembl ID		ENSG00000198883	ENSG00000241553
Uniprot IDs		Q96PV4	P59998
PDB IDs
Enriched GO Terms of Interacting Partners?
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