CHRNE and CHRNA1

Number of citations of the paper that reports this interaction (PubMedID 1712080)
15

Data Source:
HPRD (in vitro)

		CHRNE	CHRNA1
Description		cholinergic receptor nicotinic epsilon subunit	cholinergic receptor nicotinic alpha 1 subunit
Image
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Acetylcholine-gated Channel Complex Cell Junction Neuromuscular Junction Neuron Projection Synapse Integral Component Of Postsynaptic Specialization Membrane	Cell Plasma Membrane Integral Component Of Plasma Membrane Acetylcholine-gated Channel Complex Cell Surface Cell Junction Neuromuscular Junction Neuron Projection Synapse Postsynaptic Membrane Integral Component Of Postsynaptic Specialization Membrane
	Molecular Function	Cation Transmembrane Transporter Activity Acetylcholine Receptor Activity Acetylcholine-gated Cation-selective Channel Activity Acetylcholine Binding Transmitter-gated Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential	Ion Channel Activity Acetylcholine Receptor Activity Acetylcholine-gated Cation-selective Channel Activity Acetylcholine Binding Transmitter-gated Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential
	Biological Process	Muscle Contraction Signal Transduction Chemical Synaptic Transmission Synaptic Transmission, Cholinergic Neuromuscular Synaptic Transmission Ion Transmembrane Transport Response To Nicotine Regulation Of Membrane Potential Nervous System Process Excitatory Postsynaptic Potential Cation Transmembrane Transport	Skeletal Muscle Contraction Cation Transport Signal Transduction Chemical Synaptic Transmission Synaptic Transmission, Cholinergic Neuromuscular Synaptic Transmission Neuromuscular Junction Development Neuronal Action Potential Ion Transmembrane Transport Response To Nicotine Regulation Of Membrane Potential Muscle Cell Cellular Homeostasis Skeletal Muscle Tissue Growth Nervous System Process Musculoskeletal Movement Neuromuscular Process Excitatory Postsynaptic Potential Neuron Cellular Homeostasis
Pathways		Highly sodium permeable postsynaptic acetylcholine nicotinic receptors	Highly calcium permeable postsynaptic nicotinic acetylcholine receptors Highly calcium permeable nicotinic acetylcholine receptors
Drugs		Galantamine	Galantamine Agmatine
Diseases		Congenital myasthenic syndrome	Congenital myasthenic syndrome Multiple pterygium syndrome, including: Multiple pterygium syndrome, lethal type (LMPS); Multiple pterygium syndrome, Escobar variant (EVMPS)
GWAS		Platelet count ( 29403010)	Atrial fibrillation ( 29892015)
Interacting Genes		1 interacting genes: CHRNA1	4 interacting genes: CHRND CHRNE CHRNG ITGA7
Entrez ID		1145	1134
HPRD ID		00008	00007
Ensembl ID		ENSG00000108556	ENSG00000138435
Uniprot IDs		Q04844	P02708 Q53SH4
PDB IDs		2DF9	1Y5P 1Y5T 1Y6C 4ZJS 5HBT
Enriched GO Terms of Interacting Partners?
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