GABARAP and NBR1

Number of citations of the paper that reports this interaction (PubMedID 20562859)
598

Data Source:
BioGRID (pull down, affinity chromatography technology, affinity chromatography technology)

		GABARAP	NBR1
Description		GABA type A receptor-associated protein	NBR1 autophagy cargo receptor
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GO Annotations	Cellular Component	Golgi Membrane Autophagosome Membrane Lysosome Autophagosome Smooth Endoplasmic Reticulum Cytosol Microtubule Microtubule Associated Complex Plasma Membrane Axoneme Actin Cytoskeleton Cytoplasmic Vesicle Cell Body Synapse Perinuclear Region Of Cytoplasm Sperm Midpiece	Phagophore Assembly Site Nucleoplasm Mitochondrion Lysosome Late Endosome Autophagosome Cytosol Membrane Nuclear Body M Band Intracellular Membrane-bounded Organelle Receptor Complex
	Molecular Function	Protein Binding Microtubule Binding Ubiquitin Protein Ligase Binding Beta-tubulin Binding GABA Receptor Binding	Protein Binding Zinc Ion Binding Ubiquitin Binding Mitogen-activated Protein Kinase Binding
	Biological Process	Autophagosome Assembly Microtubule Cytoskeleton Organization Autophagy Of Mitochondrion Protein Targeting Cellular Response To Nitrogen Starvation Chemical Synaptic Transmission Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Macroautophagy Autophagosome Maturation	Macroautophagy Regulation Of Bone Mineralization Regulation Of Stress-activated MAPK Cascade Negative Regulation Of Osteoblast Differentiation
Pathways		Macroautophagy TBC/RABGAPs	Pexophagy Pexophagy
Drugs
Diseases
GWAS
Interacting Genes		51 interacting genes: AMBRA1 ANK2 ANK3 ATG101 ATG13 ATG3 ATG4A ATG4B ATG4C ATG4D ATG7 BIRC6 CUL3 DMPK DVL2 FLCN GABRG1 GABRG2 GABRG3 GPHN HDAC5 KBTBD7 KDR LMNB1 MAPK15 MEFV MIB1 MLH1 MPC1 NBR1 NEDD4 NSF OPTN PCM1 PGS1 PKP4 RB1CC1 RETREG1 SQSTM1 SRPK1 SRPK2 TAX1BP1 TBC1D25 TFRC TLE5 TP53INP1 TRIM21 TUBB3 ULK1 ULK2 VPS28	21 interacting genes: ATXN1L AXIN1 CALM1 CIB1 FEZ1 GABARAP GABARAPL2 GSK3A GSK3B ITSN2 MAP1LC3A MAP1LC3B MAP2K4 SQSTM1 SYT4 TTN UBC UBE2D2 UBE2D3 USP8 VTA1
Entrez ID		11337	4077
HPRD ID		05496	01326
Ensembl ID		ENSG00000170296	ENSG00000188554
Uniprot IDs		O95166 Q6IAW1	A0A024R1V3 B7Z5R6 Q14596
PDB IDs		1GNU 1KLV 1KM7 1KOT 3D32 3DOW 3WIM 4XC2 5DPS 6HB9 6HOG 6HOH 6HOJ 6HOK 6HYL 6HYM 6HYN 6HYO	1WJ6 2BKF 2CP8 2G4S 2L8J 2MGW 2MJ5 4OLE
Enriched GO Terms of Interacting Partners?
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