STK38 and SENP2

Number of citations of the paper that reports this interaction (PubMedID 29969578)
0

Data Source:
BioGRID (enzymatic study)

		STK38	SENP2
Description		serine/threonine kinase 38	SUMO specific peptidase 2
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Nucleus Nuclear Pore Nucleoplasm Cytosol PML Body Nuclear Membrane
	Molecular Function	Magnesium Ion Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Mitogen-activated Protein Kinase Kinase Kinase Binding Cadherin Binding	Protein Binding SUMO-specific Protease Activity Protein Domain Specific Binding SUMO-specific Endopeptidase Activity SUMO-specific Isopeptidase Activity
	Biological Process	Cellular Protein Modification Process Protein Phosphorylation Peptidyl-serine Phosphorylation Intracellular Signal Transduction Negative Regulation Of MAP Kinase Activity	Positive Regulation Of Protein Phosphorylation Heart Development Dorsal/ventral Axis Specification Protein Transport Wnt Signaling Pathway Protein Sumoylation Protein Desumoylation Regulation Of Wnt Signaling Pathway Negative Regulation Of Protein Ubiquitination Positive Regulation Of Protein Ubiquitination Protein Destabilization Negative Regulation Of Protein Binding Regulation Of DNA Endoreduplication Negative Regulation Of Chromatin Binding Fat Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II MRNA Transport Trophoblast Giant Cell Differentiation Labyrinthine Layer Development Spongiotrophoblast Layer Development Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways			SUMO is proteolytically processed
Drugs
Diseases
GWAS		Subclinical trait of interstitial lung disease (basilar percentage of high attenuation areas on CT scan) ( 28521775) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)	Diastolic blood pressure ( 28135244 27841878) Estimated glomerular filtration rate ( 31152163 31015462) Height ( 28552196) Hip circumference ( 28552196) PR interval ( 30046033) QRS duration ( 30012220) Seborrheic dermatitis ( 29203360) Systolic blood pressure ( 27841878 26969751)
Interacting Genes		15 interacting genes: CALM1 CTDP1 H2AC20 H2BC21 H3C6 HERC5 HRAS MOB2 S100B SENP2 TRAF3 TRIM14 TRIM25 YWHAB YWHAZ	28 interacting genes: AGTRAP APP ARL6IP1 AXIN1 CDCA5 CDK5RAP2 DAXX FUNDC1 FZR1 IKBKG KASH5 KPNA1 KPNB1 LMNA MYC NACC1 NEDD4L NUP153 PML RANGAP1 STK38 SUMO1 SUMO2 SUMO3 SYNE4 TMEM239 TPD52 TRIM63
Entrez ID		11329	59343
HPRD ID		09511	07002
Ensembl ID		ENSG00000112079	ENSG00000163904
Uniprot IDs		A0A024RD18 Q15208	Q9HC62
PDB IDs		1PSB 6BXI	1TGZ 1TH0 2IO0 2IO1 2IO2 2IO3 3ZO5 5AEK
Enriched GO Terms of Interacting Partners?
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