MED8 and MED20

Number of citations of the paper that reports this interaction (PubMedID 26344197)
117

Data Source:
BioGRID (biochemical, proximity labelling technology, affinity chromatography technology)
HPRD (in vitro)

		MED8	MED20
Description		mediator complex subunit 8	mediator complex subunit 20
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mediator Complex Core Mediator Complex	Ubiquitin Ligase Complex Nucleoplasm Mediator Complex
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Transcription Coregulator Activity Protein Binding	Transcription Coactivator Activity DNA-directed 5'-3' RNA Polymerase Activity Protein Binding Ubiquitin Protein Ligase Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Protein Ubiquitination	Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Protein Ubiquitination Positive Regulation Of Nucleic Acid-templated Transcription
Pathways		PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation	PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS		Feeling worry ( 29500382) Schizophrenia ( 28991256)	Mean corpuscular hemoglobin ( 20139978 27863252) Mean corpuscular volume ( 23263863 20139978 27863252) Metabolite levels ( 23823483) Red blood cell count ( 20139978)
Interacting Genes		31 interacting genes: APP ARRB2 CCNC CDK8 CTDP1 ELOC HSPB3 KRT40 MED1 MED11 MED12 MED17 MED19 MED20 MED22 MED25 MED26 MED27 MED28 MED30 MED31 MED6 MED7 MED9 PEX14 PHYHIP PNMA1 SNTA1 THOC7 UBALD1 USP49	7 interacting genes: CD300C ESR1 ESR2 MED18 MED29 MED8 POLR1B
Entrez ID		112950	9477
HPRD ID		06991	15638
Ensembl ID		ENSG00000159479	ENSG00000124641
Uniprot IDs		Q96G25	B3KUJ9 Q9H944
PDB IDs
Enriched GO Terms of Interacting Partners?
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