KLHL2 and TNPO2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

		KLHL2	TNPO2
Description		kelch like family member 2	transportin 2
Image			No pdb structure
GO Annotations	Cellular Component	Ruffle Cytoplasm Cytosol Actin Cytoskeleton Lamellipodium Cul3-RING Ubiquitin Ligase Complex	Nucleus Cytoplasm
	Molecular Function	Actin Binding Protein Binding Identical Protein Binding	Protein Binding Nuclear Localization Sequence Binding Ran GTPase Binding Nuclear Import Signal Receptor Activity
	Biological Process	Protein Ubiquitination Post-translational Protein Modification	Protein Import Into Nucleus
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Cognitive function ( 24684796) General cognitive ability ( 29844566) Neuroticism ( 27067015)	Diffuse large B-cell lymphoma or multiple sclerosis ( 31407831)
Interacting Genes		15 interacting genes: ACTC1 BCAM CCDC43 CLK2 CUL3 KLHL12 SDCBP TMA16 TNPO2 TXNDC12 UBE2C UBE2D1 WNK1 WNK4 ZNF114	18 interacting genes: A1CF APIP C1orf94 CAMK2D CRYAB ELAVL1 EXOC5 KLHL2 NME1 NUP98 NXF1 PIK3CD PNMA5 RAN RPL4 TCL1B TERF1 TRMT1
Entrez ID		11275	30000
HPRD ID		09311	04301
Ensembl ID		ENSG00000109466	ENSG00000105576
Uniprot IDs		B4DFZ5 E9PEX9 O95198	A0A024R7F7 O14787 Q05D48 Q4LE60
PDB IDs		2XN4 4CHB
Enriched GO Terms of Interacting Partners?
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