POLI and DAZAP2

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		POLI	DAZAP2
Description		DNA polymerase iota	DAZ associated protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Intracellular Nucleoplasm Nuclear Speck Cytoplasmic Ribonucleoprotein Granule	Cytoplasm Nuclear Speck Protein-containing Complex
	Molecular Function	Damaged DNA Binding DNA-directed DNA Polymerase Activity Protein Binding Metal Ion Binding	Protein Binding Receptor Tyrosine Kinase Binding Mitogen-activated Protein Kinase Kinase Kinase Binding Identical Protein Binding Protein Serine/threonine Kinase Activator Activity WW Domain Binding
	Biological Process	DNA Replication DNA Repair Translesion Synthesis Error-prone Translesion Synthesis	Positive Regulation Of Protein Serine/threonine Kinase Activity
Pathways		Translesion synthesis by POLI Termination of translesion DNA synthesis
Drugs
Diseases
GWAS		Asthma ( 31361310 30929738) Asthma (childhood onset) ( 30929738) Inflammatory skin disease ( 25574825)
Interacting Genes		20 interacting genes: APP CALCOCO2 DAZAP2 DVL2 EP300 MFHAS1 MTNR1B NEDD8 PCNA POLH REV1 RNF11 TMEM239 TRAF6 TRIM23 TRIM39 UBA52 UBB UBC ZBTB44	91 interacting genes: AATF ARID5A ATXN1 ATXN1L BAG3 BATF2 C1orf94 CALCOCO2 CCDC120 CDK4 CEP70 CLASRP COL4A2 COL4A5 CXCL12 DAB1 DAZ1 DAZL DCUN1D1 EPN1 EXD3 FAM168A FBN3 GPSM1 HGS HIP1 INCA1 KRTAP19-5 KRTAP8-1 LASP1 LMO2 MAGED1 MED31 NDUFA5 NEDD4 NEDD4L NOC4L NOTCH1 OPTN OTULIN PEF1 PLEKHB2 PLSCR1 POGZ POLI PRR20A RABGEF1 RBFOX1 RBFOX2 RBM11 RBPMS RHOXF2 RNF115 RNF208 ROR2 RPS27A SEPTIN2 SMAP2 SMURF2 SOX6 SQSTM1 STAM2 STAT6 TAX1BP1 TCF7L2 TENT5B TENT5C TEX37 TLE1 TNIP3 TOLLIP UBA52 UBAC1 UBASH3A UBASH3B UBB UBC UBE2D4 UBE2E2 UBE3A UBQLN4 USP5 VHLL VPS37C WDR73 WWP1 ZC3H10 ZFAND2B ZFYVE9 ZNF34 ZNF581
Entrez ID		11201	9802
HPRD ID		16094	08463
Ensembl ID		ENSG00000101751	ENSG00000183283
Uniprot IDs		Q9UNA4	A0A024R110 Q15038
PDB IDs		1T3N 1ZET 2ALZ 2DPI 2DPJ 2FLL 2FLN 2FLP 2KHU 2KHW 2KTF 2L0F 2L0G 2MBB 3EPG 3EPI 3G6V 3G6X 3G6Y 3GV5 3GV7 3GV8 3H40 3H4B 3H4D 3NGD 3OSN 3Q8P 3Q8Q 3Q8R 3Q8S 4EBC 4EBD 4EBE 4EYH 4EYI 4FS1 4FS2 5KT2 5KT3 5KT4 5KT5 5KT6 5KT7 5ULW 5ULX
Enriched GO Terms of Interacting Partners?
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