WBP4 and CPSF6

Number of citations of the paper that reports this interaction (PubMedID 16055720)
81

Data Source:
BioGRID (pull down)

		WBP4	CPSF6
Description		WW domain binding protein 4	cleavage and polyadenylation specific factor 6
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Speck U2-type Precatalytic Spliceosome Precatalytic Spliceosome	Nucleus Nucleoplasm Perichromatin Fibrils Cytoplasm MRNA Cleavage And Polyadenylation Specificity Factor Complex MRNA Cleavage Factor Complex Membrane Nuclear Speck Interchromatin Granule Paraspeckles Ribonucleoprotein Complex
	Molecular Function	Nucleic Acid Binding RNA Binding Protein Binding Zinc Ion Binding Proline-rich Region Binding	RNA Binding MRNA Binding Protein Binding Ribosomal Large Subunit Binding Exon-exon Junction Complex Binding
	Biological Process	MRNA Splicing, Via Spliceosome RNA Splicing MRNA Cis Splicing, Via Spliceosome	MRNA Processing Positive Regulation Of RNA Export From Nucleus Protein Tetramerization Protein Heterotetramerization Pre-mRNA Cleavage Required For Polyadenylation MRNA Alternative Polyadenylation Messenger Ribonucleoprotein Complex Assembly
Pathways		mRNA Splicing - Major Pathway	Signaling by cytosolic FGFR1 fusion mutants Signaling by FGFR1 in disease
Drugs
Diseases
GWAS		Crohn's disease ( 23266558) CSF tryptophan concentration in tuberculous meningitis ( 29395996) Intraocular pressure ( 29617998) Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444 31624269)	Height ( 18391951) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (diuretics) ( 31015401) Pneumoconiosis in silica exposure ( 24986923) Smoking initiation (ever regular vs never regular) ( 30679032) Smoking status (ever vs never smokers) ( 30643258)
Interacting Genes		44 interacting genes: BUB3 CAPRIN1 CHERP CHTF8 CPSF6 CPSF7 DDX23 DDX3X DHX15 DIAPH1 DNM2 EFTUD2 EWSR1 FUS HLTF HNRNPK HNRNPU HTATSF1 KHDRBS1 NONO PABPC1 PRPF3 PRPF4 PRPF40A PSPC1 SART1 SCAF4 SF1 SF3A1 SF3A2 SF3A3 SF3B1 SF3B3 SF3B4 SFPQ SNRNP70 SNRPA SNRPB TCERG1 WAS WBP11 WIPF1 XRCC6 ZNF207	23 interacting genes: APBB1 ARMC7 CSNK2A1 EWSR1 GIN1 ITCH ITSN2 KLHL12 NCK2 NEDD4 NUDT21 OTUB2 PLSCR1 PPIL1 PRPF40A SRSF7 TCERG1 TOLLIP UBAC1 UBQLN4 WBP4 WWP1 WWP2
Entrez ID		11193	11052
HPRD ID		16086	05401
Ensembl ID		ENSG00000120688	ENSG00000111605
Uniprot IDs		O75554	Q16630
PDB IDs		2DK1 2JXW 5O9Z 6AHD	3P5T 3P6Y 3Q2S 3Q2T 4B4N 4U0A 4U0B 4WYM 6AY9 6GX9
Enriched GO Terms of Interacting Partners?
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