TLK2 and ASF1A

Number of citations of the paper that reports this interaction (PubMedID 11470414)
74

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		TLK2	ASF1A
Description		tousled like kinase 2	anti-silencing function 1A histone chaperone
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GO Annotations	Cellular Component	Nucleus Intermediate Filament Perinuclear Region Of Cytoplasm	Nuclear Chromatin Nucleus Nucleoplasm Protein-containing Complex
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding	Chromatin Binding Protein Binding Histone Binding
	Biological Process	Regulation Of Chromatin Assembly Or Disassembly Chromatin Organization Protein Phosphorylation Cellular Response To DNA Damage Stimulus Cell Cycle Chromosome Segregation Negative Regulation Of Autophagy Peptidyl-serine Phosphorylation Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Intracellular Signal Transduction Cellular Response To Gamma Radiation	Osteoblast Differentiation DNA Repair Nucleosome Assembly DNA Replication-dependent Nucleosome Assembly DNA Replication-independent Nucleosome Assembly Negative Regulation Of Chromatin Silencing Muscle Cell Differentiation
Pathways			Formation of Senescence-Associated Heterochromatin Foci (SAHF)
Drugs
Diseases
GWAS		Heel bone mineral density ( 30598549) Lifespan ( 25918517)	Multiple sclerosis ( 31604244) QT interval ( 19305408)
Interacting Genes		11 interacting genes: ASF1A ASF1B AURKA DCAF7 FEZ1 FEZ2 IRF4 IRF7 MBP TLK1 YWHAZ	22 interacting genes: ASF1B CDAN1 CHAF1A CHAF1B CHEK2 H3-3A H3-4 H3C3 H3C6 H4-16 H4C13 H4C6 HIRA HTATIP2 PAFAH1B2 PRR3 ST13 TAF1 TLK1 TLK2 VPS28 ZDHHC17
Entrez ID		11011	25842
HPRD ID		10527	16459
Ensembl ID		ENSG00000146872	ENSG00000111875
Uniprot IDs		B4DUC2 J3QLK5 Q86UE8	Q9Y294
PDB IDs		5O0Y	1TEY 2I32 2IIJ 2IO5 3AAD 5C3I 6F0F 6F0G 6F0H
Enriched GO Terms of Interacting Partners?
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