OS9 and FAIM2

		OS9	FAIM2
Description		OS9 endoplasmic reticulum lectin	Fas apoptotic inhibitory molecule 2
Image			No pdb structure
GO Annotations	Cellular Component	Hrd1p Ubiquitin Ligase Complex Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Endoplasmic Reticulum Quality Control Compartment	Endoplasmic Reticulum Golgi Apparatus Integral Component Of Membrane Cell Junction Membrane Raft Postsynaptic Membrane
	Molecular Function	Protease Binding Protein Binding Carbohydrate Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Targeting Protein Retention In ER Lumen Protein Ubiquitination Ubiquitin-dependent ERAD Pathway Retrograde Protein Transport, ER To Cytosol Response To Endoplasmic Reticulum Stress Transmembrane Transport Negative Regulation Of Retrograde Protein Transport, ER To Cytosol Endoplasmic Reticulum Mannose Trimming	Response To Ischemia Apoptotic Process Cerebellum Development Cerebellar Purkinje Cell Layer Development Cerebellar Granular Layer Development Cerebellar Purkinje Cell Differentiation Negative Regulation Of Apoptotic Process Regulation Of Neuron Apoptotic Process Negative Regulation Of Neuron Apoptotic Process Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Pathways		ABC-family proteins mediated transport Hedgehog ligand biogenesis Hh mutants that don't undergo autocatalytic processing are degraded by ERAD Defective CFTR causes cystic fibrosis ER Quality Control Compartment (ERQC)
Drugs
Diseases
GWAS		Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Multiple sclerosis ( 31604244) Rheumatoid arthritis (ACPA-positive) ( 24532676)	Alcohol consumption (drinks per week) ( 30643258) Blood urea nitrogen levels ( 31152163) BMI (adjusted for smoking behaviour) ( 28443625) BMI in non-smokers ( 28443625) BMI in smokers ( 28443625) Body fat mass ( 28552196) Body mass index ( 28552196 19079260 28892062 20935630 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Body mass index in physically active individuals ( 28448500) Body mass index in physically inactive individuals ( 28448500) Breast size ( 27182965) Childhood body mass index ( 26604143) Hip circumference ( 28552196 25673412) Menarche (age at onset) ( 27182965) Obese vs. thin ( 30677029) Obesity (extreme) ( 30677029) Obsessive-compulsive disorder ( 22889921) Trunk fat mass ( 28552196) Urate levels ( 31578528) Waist circumference ( 28552196 19557197) Weight ( 28552196 19079260)
Interacting Genes		27 interacting genes: ACP1 ACVR1B CPNE6 CREB3 DCSTAMP EGLN1 EGLN3 EIF6 FAIM2 FOXM1 GLS2 HIF1A HSP90B1 LINC00839 MEP1B P3H3 PGD PTH RBX1 SCN8A SLC22A1 SMAD2 SNRPD2 SREBF2 TRPV4 UVRAG ZNF512B	3 interacting genes: FAS OS9 STK11
Entrez ID		10956	23017
HPRD ID		17804	09184
Ensembl ID		ENSG00000135506	ENSG00000135472
Uniprot IDs		Q13438	Q9BWQ8
PDB IDs		3AIH
Enriched GO Terms of Interacting Partners?
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