RUNDC3A and GEM

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		RUNDC3A	GEM
Description		RUN domain containing 3A	GTP binding protein overexpressed in skeletal muscle
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane	Cell Nucleus Plasma Membrane Cytoplasmic Side Of Plasma Membrane Midbody Spindle Midzone Mitotic Spindle
	Molecular Function	Protein Binding GTPase Regulator Activity	Magnesium Ion Binding GTPase Activity Calcium Channel Regulator Activity Protein Binding Calmodulin Binding GTP Binding GDP Binding
	Biological Process	Small GTPase Mediated Signal Transduction Positive Regulation Of CGMP-mediated Signaling Regulation Of Catalytic Activity	Mitotic Cell Cycle Immune Response Signal Transduction Cell Surface Receptor Signaling Pathway Chromosome Organization Metaphase Plate Congression Negative Regulation Of High Voltage-gated Calcium Channel Activity
Pathways
Drugs
Diseases
GWAS			Carotid plaque burden ( 28282560) Coronary artery disease ( 29212778) Pulse pressure ( 30578418)
Interacting Genes		23 interacting genes: AP1M1 AP2M1 ARMC7 CCNL2 DDX6 EIF3E FAM161A GEM GFI1B MAGEB4 MAGOHB MRPL15 MYO15B RAP1A RAP2A RAP2B SDCBP SYT17 TBRG1 TEAD4 TFPT ZNF417 ZNF587	41 interacting genes: A2M AHCYL1 APOH BLZF1 BMP1 CALM1 CCDC102B CLDN15 CLEC4G COG8 CTSL DEUP1 GMIP GOLGA2 IKZF3 INO80E KCTD9 KLC3 KRT31 KRT40 KRTAP10-3 KRTAP10-7 LZTS2 NDUFAF3 NDUFS8 NOTCH2NLA PDLIM7 PNMA1 RNF7 RUNDC3A SDHB SSX2IP TCF4 TFIP11 TRAF1 TRIM23 TRIM27 TRIM54 VTN YBEY YWHAB
Entrez ID		10900	2669
HPRD ID		16106	11553
Ensembl ID		ENSG00000108309	ENSG00000164949
Uniprot IDs		Q59EK9	A0A024R9F5 P55040
PDB IDs			2CJW 2G3Y 2HT6
Enriched GO Terms of Interacting Partners?
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