CPLX2 and STX2

Number of citations of the paper that reports this interaction (PubMedID 10777504)
64

Data Source:
HPRD (in vivo, in vitro)

		CPLX2	STX2
Description		complexin 2	syntaxin 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Cell Junction Dendrite SNARE Complex Mast Cell Granule Terminal Bouton Perikaryon Calyx Of Held Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II Complex Synaptobrevin 2-SNAP-25-syntaxin-3-complexin Complex Postsynapse Glutamatergic Synapse	Extracellular Space Plasma Membrane Synaptic Vesicle Endomembrane System Integral Component Of Membrane Basolateral Plasma Membrane Lamellipodium SNARE Complex Protein-containing Complex Presynaptic Membrane Intracellular Membrane-bounded Organelle Presynaptic Active Zone Membrane
	Molecular Function	SNARE Binding Syntaxin-1 Binding Calcium-dependent Protein Binding	SNARE Binding Structural Molecule Activity SNAP Receptor Activity Protein Binding Calcium-dependent Protein Binding
	Biological Process	Vesicle Docking Involved In Exocytosis Nervous System Development Synaptic Vesicle Exocytosis Regulation Of Exocytosis Cell Differentiation Regulation Of Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Positive Regulation Of Synaptic Plasticity Mast Cell Degranulation Regulation Of Neurotransmitter Secretion	Intracellular Protein Transport Exocytosis Vesicle Fusion Signal Transduction Acrosome Reaction Ectoderm Development Animal Organ Morphogenesis Cell Differentiation Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Cellular Response To Oxidative Stress Vesicle Docking Cornified Envelope Assembly
Pathways
Drugs
Diseases
GWAS		Age-related nuclear cataracts ( 24951543) Chronotype ( 30696823) Obesity-related traits ( 23251661)	Initial pursuit acceleration in psychotic disorders ( 29064472) Metabolite levels ( 23823483) Plasma plasminogen activator levels ( 24578379) vWF levels ( 30586737)
Interacting Genes		3 interacting genes: APP STX2 STX3	10 interacting genes: CPLX2 SNAP25 STXBP1 STXBP2 SYT1 SYT4 SYT7 UNC13B VAMP3 VAPB
Entrez ID		10814	2054
HPRD ID		09234	11816
Ensembl ID		ENSG00000145920	ENSG00000111450
Uniprot IDs		Q6PUV4	P32856
PDB IDs
Enriched GO Terms of Interacting Partners?
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