B3GNT2 and C1GALT1C1

Number of citations of the paper that reports this interaction (PubMedID 26186194)
367

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology)
HPRD (in vitro)

		B3GNT2	C1GALT1C1
Description		UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	C1GALT1 specific chaperone 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Golgi Apparatus Integral Component Of Membrane	Golgi Membrane Integral Component Of Membrane Extracellular Exosome
	Molecular Function	Protein Binding Acetylglucosaminyltransferase Activity Acetylgalactosaminyltransferase Activity Galactosyltransferase Activity Beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide Beta-1,3-acetylglucosaminyltransferase Activity N-acetyllactosaminide Beta-1,3-N-acetylglucosaminyltransferase Activity Transferase Activity, Transferring Hexosyl Groups	Protein Binding Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase Activity
	Biological Process	Protein Glycosylation Protein O-linked Glycosylation Axon Guidance Sensory Perception Of Smell O-glycan Processing Keratan Sulfate Biosynthetic Process Poly-N-acetyllactosamine Biosynthetic Process Cellular Response To Leukemia Inhibitory Factor	Protein O-linked Glycosylation O-glycan Processing O-glycan Processing, Core 1 Platelet Activation Platelet Morphogenesis
Pathways		Keratan sulfate biosynthesis O-linked glycosylation of mucins	Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) O-linked glycosylation of mucins
Drugs
Diseases
GWAS		Ankylosing spondylitis ( 20062062) Blood protein levels ( 30072576) Iron status biomarkers (total iron binding capacity) ( 28334935) Mean corpuscular hemoglobin concentration ( 29403010) Mean corpuscular volume ( 29403010) Psoriasis ( 25903422 23143594) Psoriasis vulgaris ( 26626624) Rheumatoid arthritis ( 30423114 22446963 24390342)	Serum galactose-deficient IgA1 levels ( 28187132)
Interacting Genes		2 interacting genes: C1GALT1C1 PGAP4	3 interacting genes: B3GNT2 C1GALT1 LGALS3
Entrez ID		10678	29071
HPRD ID		09279	06462
Ensembl ID		ENSG00000170340	ENSG00000171155
Uniprot IDs		Q9NY97	Q96EU7
PDB IDs
Enriched GO Terms of Interacting Partners?
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