DRAP1 and PLEKHF2

Number of citations of the paper that reports this interaction (PubMedID 21516116)
94

Data Source:
BioGRID (two hybrid)

		DRAP1	PLEKHF2
Description		DR1 associated protein 1	pleckstrin homology and FYVE domain containing 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus	Endoplasmic Reticulum Transport Vesicle Early Endosome Membrane
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA Binding DNA-binding Transcription Factor Activity Transcription Coregulator Activity Transcription Corepressor Activity Protein Binding Identical Protein Binding Protein Heterodimerization Activity	Protein Binding Phosphatidylinositol Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated	Protein Transport
Pathways		Signaling by NODAL Signaling by Activin
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Eosinophil percentage of granulocytes ( 27863252) Multiple sclerosis ( 31604244) Neutrophil percentage of granulocytes ( 27863252) Severe influenza A (H1N1) infection ( 26379185)	Radiation response ( 20923822)
Interacting Genes		26 interacting genes: APP ARHGEF10L CDKN2C DNAJB11 DR1 FBXO7 FEZ1 FEZ2 FOXH1 GTF2B LMO2 LNX2 NCK2 NFYB PIK3R3 PLEKHF2 POLE3 SDCBP SRPK2 TAF9 TAF9B TBP TK1 TNFRSF14 TTF2 ZEB1	71 interacting genes: ACY3 AIDA AIMP2 APP APPL1 ARL14EP BEND7 BLOC1S6 BSCL2 CAVIN2 CCDC172 CCDC85B CEP44 CGGBP1 CHIC2 DPPA4 DRAP1 DTX2 DUT ESRP1 FBXO28 FHL3 FOXA1 FRMD8 GFER GLUL GNMT GPBP1 GPBP1L1 HEY1 HSPB7 L3MBTL3 LDOC1 MAX MBIP MEAF6 NKG7 NONO NPM2 PDP1 PEX2 PRDM14 PRKAR1A PRPSAP1 RAB39A RABAC1 RADX RSPO2 RTN1 RTN3 RTN4 S100A1 S100A13 SEPTIN2 SEPTIN5 SEPTIN6 SETBP1 SFN SPEF1 TBX3 TCN2 TNFAIP8 TRAF6 TRAPPC3 TSC22D3 TXNL4B UBE2Z USF1 ZNF250 ZNF263 ZNF398
Entrez ID		10589	79666
HPRD ID		03796	15147
Ensembl ID		ENSG00000175550	ENSG00000175895
Uniprot IDs		Q14919	Q9H8W4
PDB IDs		1JFI
Enriched GO Terms of Interacting Partners?
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