CENPA and HJURP

Number of citations of the paper that reports this interaction (PubMedID 26496610)
285

Data Source:
BioGRID (pull down, affinity chromatography technology, affinity chromatography technology)

		CENPA	HJURP
Description		centromere protein A	Holliday junction recognition protein
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GO Annotations	Cellular Component	Chromosome, Centromeric Region Condensed Nuclear Chromosome Kinetochore Condensed Nuclear Chromosome, Centromeric Region Nuclear Nucleosome Condensed Chromosome Inner Kinetochore Cell Nucleus Nucleoplasm Cytosol Nuclear Pericentric Heterochromatin	Chromosome, Centromeric Region Condensed Chromosome Kinetochore Nucleoplasm Nucleolus Mitochondrion
	Molecular Function	DNA Binding Chromatin Binding Protein Binding Protein Heterodimerization Activity	DNA Binding Protein Binding Histone Binding Identical Protein Binding
	Biological Process	Establishment Of Mitotic Spindle Orientation Mitotic Cytokinesis Viral Process CENP-A Containing Nucleosome Assembly Kinetochore Assembly Protein Localization To Chromosome, Centromeric Region	Cell Cycle Chromosome Segregation CENP-A Containing Nucleosome Assembly Regulation Of Protein Complex Assembly Regulation Of DNA Binding
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation	Deposition of new CENPA-containing nucleosomes at the centromere
Drugs
Diseases
GWAS			Hair greying ( 26926045) Headache ( 29397368) Migraine ( 27322543) Migraine without aura ( 27322543) Total bilirubin levels in HIV-1 infection ( 25884002)
Interacting Genes		11 interacting genes: AURKB AURKC CDKN2A CUL4A DIAPH1 DIAPH2 H3C3 H4C6 HJURP PARP1 PARP2	6 interacting genes: CENPA H4C1 IMMT MIS18A OIP5 STT3A
Entrez ID		1058	55355
HPRD ID		00313	10912
Ensembl ID		ENSG00000115163	ENSG00000123485
Uniprot IDs		P49450	Q8NCD3
PDB IDs		3AN2 3NQJ 3NQU 3R45 3WTP 5CVD 5Z23 6BUZ 6C0W 6E0C 6E0P 6MUO 6MUP 6O1D 6SE0 6SE6 6SEE 6SEF 6SEG	3R45
Enriched GO Terms of Interacting Partners?
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