UBD and UBA6

Number of citations of the paper that reports this interaction (PubMedID 20975683)
26

Data Source:
BioGRID (affinity chromatography technology, imaging technique, enzymatic study, two hybrid)

		UBD	UBA6
Description		ubiquitin D	ubiquitin like modifier activating enzyme 6
Image			No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Cytoplasm Cytosol Aggresome	Nucleus Cytoplasm Cytosol
	Molecular Function	Protein Binding Proteasome Binding	Ubiquitin Activating Enzyme Activity Protein Binding ATP Binding FAT10 Activating Enzyme Activity
	Biological Process	Proteolysis Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Protein Modification By Small Protein Conjugation Response To Interferon-gamma Response To Tumor Necrosis Factor Myeloid Dendritic Cell Differentiation Positive Regulation Of Apoptotic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Post-translational Protein Modification Aggresome Assembly Regulation Of Mitotic Cell Cycle Phase Transition	Ubiquitin-dependent Protein Catabolic Process Cellular Response To DNA Damage Stimulus Learning Locomotory Behavior Protein Ubiquitination Amygdala Development Hippocampus Development Protein Modification By Small Protein Conjugation Dendritic Spine Development
Pathways		Neddylation	Synthesis of active ubiquitin: roles of E1 and E2 enzymes Synthesis of active ubiquitin: roles of E1 and E2 enzymes Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Crohn's disease ( 22412388) Height ( 25429064)	Regular attendance at a pub or social club ( 29970889)
Interacting Genes		11 interacting genes: MAD2L1 NUB1 OTUB1 PSMD4 SRPK1 SRPK2 TGFBR1 UBA6 UBE2D2 UBE2Z USP16	15 interacting genes: HMBOX1 LMO2 OTUB1 SMAD9 UBC UBD UBE2D1 UBE2D2 UBE2D3 UBE2G2 UBE2L3 UBE2L6 UBE2S UBE2T UBE2Z
Entrez ID		10537	55236
HPRD ID		09354	13341
Ensembl ID		ENSG00000213886	ENSG00000033178
Uniprot IDs		A0A1U9X8S6 O15205	A0AVT1 A1LT96
PDB IDs		2MBE 6GF1 6GF2
Enriched GO Terms of Interacting Partners?
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