TRIM22 and CIC

Number of citations of the paper that reports this interaction (PubMedID 16713569)
313

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TRIM22	CIC
Description		tripartite motif containing 22	capicua transcriptional repressor
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Cajal Body Nuclear Body Nuclear Speck	Nuclear Chromatin Nucleus Nucleoplasm Protein-containing Complex Intracellular Membrane-bounded Organelle
	Molecular Function	Transcription Corepressor Activity Protein Binding Zinc Ion Binding Transferase Activity Protein Kinase Binding Protein Binding, Bridging Identical Protein Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding Protein Binding
	Biological Process	Regulation Of Transcription, DNA-templated Immune Response Response To Virus Positive Regulation Of Autophagy Viral Process Protein Ubiquitination Regulation Of Protein Localization Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Defense Response To Virus Interferon-gamma-mediated Signaling Pathway Negative Regulation Of Nucleic Acid-templated Transcription	Negative Regulation Of Transcription By RNA Polymerase II Brain Development Learning Memory Social Behavior Negative Regulation Of Transcription, DNA-templated Lung Alveolus Development
Pathways		Interferon gamma signaling
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778)	Bitter alcoholic beverage consumption ( 31046077)
Interacting Genes		10 interacting genes: CASK CIC CREB1 LGALS3 LGALS8 MFHAS1 RERE TAF7 USP7 ZZZ3	14 interacting genes: ATXN1 CENPJ CSNK2B GABPB1 GTPBP3 NFYC PICK1 PLD3 PLK1 PYCR2 SEC62 SETD2 TRIM22 ZNRD1
Entrez ID		10346	23152
HPRD ID		05951	10831
Ensembl ID		ENSG00000132274	ENSG00000079432
Uniprot IDs		B4DQS5 Q8IYM9	A0A0A0MQR4 Q96RK0
PDB IDs			2M41 4J2J 4J2L 6JRP
Enriched GO Terms of Interacting Partners?
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