CWC27 and FRA10AC1

Number of citations of the paper that reports this interaction (PubMedID 22365833)
132

Data Source:
BioGRID (two hybrid)

		CWC27	FRA10AC1
Description		CWC27 spliceosome associated cyclophilin	FRA10A associated CGG repeat 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome	Nucleus
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Cyclosporin A Binding	Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome Protein Peptidyl-prolyl Isomerization Protein Folding
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Bladder cancer ( 27206850) Central corneal thickness ( 31798171 29760442) Diverticular disease ( 30177863) Glucocorticoid-induced osteonecrosis (age 10 years and older) ( 26265699) Obesity-related traits ( 23251661) Systolic blood pressure ( 30224653) Urinary albumin excretion ( 30220432) Urinary albumin excretion (no hypertensive medication) ( 30220432) Urinary albumin-to-creatinine ratio ( 31630189 31511532)	Cerebrospinal AB1-42 levels in mild cognitive impairment ( 29274321) Cerebrospinal fluid AB1-42 levels ( 26252872 29274321)
Interacting Genes		10 interacting genes: CLK1 ERBIN FRA10AC1 GTF2H2 HMGA1 NLN PPWD1 RNF180 SGTB TRAPPC13	27 interacting genes: ADPRS C7orf25 CHERP CWC27 EEF1D ESS2 GATD3A GDPD2 GLRX3 HABP4 IK KASH5 MAP3K12 MFAP1 NKAP PLPPR4 PRPF3 PRPF40A SAP30BP SF3B2 THOC1 TRIM41 TTC14 U2AF1 VPS29 ZCCHC10 ZNF830
Entrez ID		10283	118924
HPRD ID		11541	12319
Ensembl ID		ENSG00000153015	ENSG00000148690
Uniprot IDs		D6REK3 Q6UX04	Q70Z53
PDB IDs		2HQ6 4R3E 5Z56 5Z58 6FF4 6FF7
Enriched GO Terms of Interacting Partners?
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