ABCC4 and SLC9A3R2

Number of citations of the paper that reports this interaction (PubMedID 18045536)
83

Data Source:
BioGRID (pull down)

		ABCC4	SLC9A3R2
Description		ATP binding cassette subfamily C member 4	SLC9A3 regulator 2
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Integral Component Of Membrane Basolateral Plasma Membrane Apical Plasma Membrane Platelet Dense Granule Membrane External Side Of Apical Plasma Membrane	Nucleus Plasma Membrane Focal Adhesion Endomembrane System Apical Plasma Membrane Extracellular Exosome
	Molecular Function	Protein Binding ATP Binding Efflux Transmembrane Transporter Activity ATPase Activity, Coupled To Transmembrane Movement Of Ions, Phosphorylative Mechanism 15-hydroxyprostaglandin Dehydrogenase (NAD+) Activity ATPase Activity ATPase Activity, Coupled To Transmembrane Movement Of Substances Xenobiotic Transmembrane Transporter Activity	Signaling Receptor Binding Protein Binding Beta-catenin Binding Protein C-terminus Binding Phosphatase Binding Cadherin Binding Molecular Adaptor Activity
	Biological Process	Platelet Degranulation Response To Organonitrogen Compound Response To Organic Cyclic Compound Prostaglandin Secretion Ion Transmembrane Transport Response To Drug Xenobiotic Transport Positive Regulation Of Smooth Muscle Cell Proliferation Transmembrane Transport Oxidation-reduction Process Cilium Assembly Export Across Plasma Membrane	Protein-containing Complex Assembly
Pathways		Platelet degranulation ABC-family proteins mediated transport
Drugs		ATP
Diseases
GWAS		Acute post-radiotherapy pain in breast cancer ( 31196165) Airway responsiveness in chronic obstructive pulmonary disease ( 25514360) Blood metabolite levels ( 24816252) Breast cancer ( 17903305) Longevity ( 20834067) Parent of origin effect on language impairment (paternal) ( 24571439) Platelet count ( 22139419 29403010 27863252) Plateletcrit ( 27863252) Response to irinotecan and platinum-based chemotherapy in non-small-cell lung cancer ( 23478653)	Diastolic blood pressure ( 27841878 30578418) Pulse pressure ( 30578418) Systolic blood pressure ( 27841878 30578418)
Interacting Genes		6 interacting genes: ERBIN MPP1 PDZK1 SLC9A3R1 SLC9A3R2 SNTA1	37 interacting genes: ABCC4 ACTN4 ADORA2B ADRB2 ATP2B2 CFTR EZR KCNJ1 LPAR1 LPAR2 P2RY1 PDGFRB PDPK1 PDZK1 PLCB3 PODXL PRKACA PRKCA PTEN PTH1R RDX RPS6KA1 SGK1 SGK3 SIAH1 SLC22A4 SLC22A5 SLC22A9 SLC26A3 SLC34A1 SLC9A3 SLCO1A2 SLCO3A1 SRY TAZ TBC1D10A WWTR1
Entrez ID		10257	9351
HPRD ID		05583	05946
Ensembl ID		ENSG00000125257	ENSG00000065054
Uniprot IDs		A8K2Q2 O15439	Q15599
PDB IDs			2D11 2HE4 2OCS 4P0C
Enriched GO Terms of Interacting Partners?
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