STAM2 and L3MBTL2

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		STAM2	L3MBTL2
Description		signal transducing adaptor molecule 2	L3MBTL histone methyl-lysine binding protein 2
Image
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Early Endosome Membrane ESCRT-0 Complex Intracellular Membrane-bounded Organelle	Nucleus Nucleoplasm
	Molecular Function	Protein Binding	Protein Binding Zinc Ion Binding Methylated Histone Binding Histone Binding
	Biological Process	Intracellular Protein Transport Endosomal Transport Macroautophagy Protein Deubiquitination Multivesicular Body Assembly Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Membrane Organization	Chromatin Organization Regulation Of Transcription, DNA-templated Negative Regulation Of G0 To G1 Transition
Pathways		EGFR downregulation Ub-specific processing proteases Negative regulation of MET activity Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis InlB-mediated entry of Listeria monocytogenes into host cell Endosomal Sorting Complex Required For Transport (ESCRT)	SUMOylation of chromatin organization proteins Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS		Adverse response to chemotherapy in breast cancer (alopecia) ( 24025145) Metabolic syndrome ( 31170924) Pulse pressure ( 30224653)	Adventurousness ( 30643258) anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Crohn's disease ( 26192919) Depression ( 29700475) General risk tolerance (MTAG) ( 30643258) Inflammatory bowel disease ( 26192919) Major depressive disorder ( 27479909) Neuroticism ( 29255261 27918536) Schizophrenia ( 25056061 29483656)
Interacting Genes		35 interacting genes: ABI2 ARRDC3 ATXN1 CBX5 DAZAP2 EGFR EPS15 FAM189A2 HGS ITCH JAK1 JAK2 JAK3 KLHL42 L3MBTL2 LCP2 LITAF MAP3K1 PHF10 PLEKHB2 PTPN1 RNF11 SH2D4A STAMBP TIMM8A TYK2 UBC UBE2D1 UBE2D2 UBE2D3 UBE2H UBQLN4 USP8 VPS37C XRN1	17 interacting genes: BEND7 CYB5R3 H3C1 H4C1 LNX2 MEAF6 MPP3 PAICS PHF10 PIAS1 STAC3 STAM2 TBC1D9B TLE5 TRIM42 ZFP64 ZFY
Entrez ID		10254	83746
HPRD ID		05876	13954
Ensembl ID		ENSG00000115145	ENSG00000100395
Uniprot IDs		O75886	A0A0S2Z5X6 Q969R5
PDB IDs		1X2Q 1X5B 2L0T 5CRV 5IXF	2W0T 3CEY 3F70
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?