CALCOCO2 and GABARAPL2

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (affinity chromatography technology)
HPRD (two hybrid)

		CALCOCO2	GABARAPL2
Description		calcium binding and coiled-coil domain 2	GABA type A receptor associated protein like 2
Image
GO Annotations	Cellular Component	Autophagosome Membrane Nucleus Cytoplasm Autophagosome Cytosol Cytoskeleton Membrane PML Body Cytoplasmic Vesicle Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm	Golgi Membrane Autophagosome Membrane Intracellular Cytoplasm Autophagosome Golgi Apparatus Cytosol Cytoplasmic Vesicle
	Molecular Function	Protein Binding Protein Homodimerization Activity Metal Ion Binding	SNARE Binding Protein Binding Microtubule Binding Ubiquitin Protein Ligase Binding Beta-tubulin Binding GABA Receptor Binding ATPase Binding
	Biological Process	Viral Process Response To Interferon-gamma Xenophagy Positive Regulation Of Autophagosome Maturation	Autophagosome Assembly Autophagy Of Mitochondrion Intra-Golgi Vesicle-mediated Transport Autophagy Cellular Response To Nitrogen Starvation Protein Transport Macroautophagy Positive Regulation Of ATPase Activity Autophagosome Maturation Negative Regulation Of Proteasomal Protein Catabolic Process
Pathways			Macroautophagy TBC/RABGAPs
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Chronotype ( 30696823) Type 2 diabetes ( 29358691 29632382) Type 2 diabetes (adjusted for BMI) ( 29632382)	Blood protein levels ( 30072576) Pancreatic cancer ( 25086665)
Interacting Genes		150 interacting genes: ABLIM1 ADSL AKAP17A AMMECR1 AP5B1 APEX2 ARHGEF39 ARHGEF5 ARNT2 ATG5 AXIN1 BAHD1 BCL6B BEX2 CBX8 CCDC185 CCDC33 CCNH CEP57L1 CHCHD3 CPNE7 CWF19L2 DAXX DAZAP2 DBNDD2 DCTN4 DCX DDIT4L DDX6 DOCK2 DUSP12 DUSP26 EEF1E1 ELOA2 ENKD1 EXOSC5 FAM107A FAM161A FAM168A FAM189A2 FAM90A1 FARS2 FASTK FBF1 FBXL18 FKBPL FNDC11 FXR2 GABARAPL1 GABARAPL2 GATAD2B GEMIN4 GIT2 GLYCTK HDAC7 HLX HNRNPLL HOXB9 IKBKG KANSL1 KAT7 KLHL42 LENG1 LGALS8 LIMS2 LITAF LMF2 LMO2 LMO4 LNX1 LONRF1 LSM4 MAGOHB MAVS MCM10 METTL17 MID2 MOS MTPAP MVP MXI1 MYH6 MYO6 NAA10 NDN NFU1 ORC5 PCGF1 PEF1 PEG10 PFDN5 PHF1 PIAS4 POLI POLR2A PPP1R18 PRKAB2 PRPF31 PSMA1 PSME4 PTBP1 PTBP2 RAB35 RABL6 RB1CC1 RBM15 RHPN1 RIN1 RNF11 RPA2 RPL9 RPS27A RTN4IP1 RTP5 RXRB SDCBP SHC1 SLC15A3 SMARCD1 SMCP SNRPB SPATA24 SRI STK16 TBC1D22B TBK1 TBRG4 TCL1A TEKT3 TENT2 TLE5 TP53RK TRAF2 TRAF4 TRAF6 TTC23L UBAC2 VARS1 VPS72 ZC2HC1C ZNF101 ZNF205 ZNF337 ZNF408 ZNF426 ZNF451 ZNF564 ZNF581 ZNF638 ZNF688	66 interacting genes: AAMP AGTRAP AHNAK2 AMBRA1 ANK2 APP ARFGAP1 ATG13 ATG3 ATG4A ATG4B ATG4D ATG7 BCL2L13 CALCOCO1 CALCOCO2 CLN8 CUL3 EGFR FUNDC1 GIMAP6 GOSR1 GPR37 KASH5 KBTBD6 KBTBD7 KIAA1958 KLHL5 KRTAP10-7 KRTAP10-9 LRSAM1 MAP1LC3B MCPH1 MEFV MLX NBR1 NEDD4 NSF OPTN OSBPL7 PRKAR2A PTPRA RAP1A RAP2A RB1CC1 RCN2 RPS2 SGTA SIK2 SQSTM1 TAX1BP1 TBC1D25 TBC1D5 TBC1D9 TBC1D9B TNIP1 TP53INP1 TP53INP2 TRIM21 TSR2 UBA5 ULK1 ULK2 VDR WDFY3 YWHAZ
Entrez ID		10241	11345
HPRD ID		06846	16246
Ensembl ID		ENSG00000136436	ENSG00000034713
Uniprot IDs		Q13137	P60520
PDB IDs		2MXP 3VVV 3VVW 4GXL 4HAN 4XKL 5AAQ 5Z7A 5Z7L	4CO7
Enriched GO Terms of Interacting Partners?
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