PATJ and KCNJ15

Number of citations of the paper that reports this interaction (PubMedID 9647694)
28

Data Source:
HPRD (in vitro, two hybrid, in vivo)

		PATJ	KCNJ15
Description		PATJ crumbs cell polarity complex component	potassium inwardly rectifying channel subfamily J member 15
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Centrosome Cytosol Plasma Membrane Bicellular Tight Junction Apical Plasma Membrane Cell Junction Centriolar Satellite Perinuclear Region Of Cytoplasm Extracellular Exosome	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Protein Binding	Inward Rectifier Potassium Channel Activity Protein Binding
	Biological Process	Intracellular Signal Transduction Bicellular Tight Junction Assembly	Potassium Ion Transport Regulation Of Ion Transmembrane Transport Potassium Ion Import Across Plasma Membrane
Pathways			Activation of G protein gated Potassium channels Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Drugs			Yohimbine
Diseases
GWAS		3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30582445) Excessive daytime sleepiness ( 27992416) Sleep traits (multi-trait analysis) ( 27992416) Type 2 diabetes ( 30297969)	Height ( 31562340) Metabolite levels ( 23823483) Non-response to antidepressants and depression ( 27622933)
Interacting Genes		28 interacting genes: ADGRB1 ASIC3 CACNG2 CLDN1 CNKSR2 CRB3 CRIPT DDX18 GLS2 GRIN2A GRIN2B GRIN2C GRIN2D KCNA4 KCNJ10 KCNJ15 KCNJ2 KIF1B MAPK12 MPP5 NLGN2 NRXN2 PARD3 PAX6 PRDM16 SCN4A SCN5A TJP3	5 interacting genes: IL16 KCNJ16 MTCH1 PATJ SNTA1
Entrez ID		10207	3772
HPRD ID		04434	03659
Ensembl ID		ENSG00000132849	ENSG00000157551
Uniprot IDs			Q99712
PDB IDs
Enriched GO Terms of Interacting Partners?
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