ADAM10 and EPHA3

  • Number of citations of the paper that reports this interaction (PubMedID 16239146)
  • 151
  • Data Source:
  • HPRD (in vitro)

ADAM10

EPHA3

Description ADAM metallopeptidase domain 10 EPH receptor A3
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease (late onset) ( 30820047)
  • Alzheimer's disease or family history of Alzheimer's disease ( 30617256)
  • Chronotype ( 30696823)
  • Diffusing capacity of carbon monoxide ( 30694715)
  • Family history of Alzheimer's disease ( 30617256)
  • Metabolite levels ( 23823483)
  • Schizophrenia ( 30285260)
  • Atrial fibrillation ( 30061737 29892015)
  • BMI (adjusted for smoking behaviour) ( 28443625)
  • BMI in non-smokers ( 28443625)
  • Body mass index (joint analysis main effects and smoking interaction) ( 28443625)
  • Diastolic blood pressure ( 27841878)
  • Loneliness (multivariate analysis) ( 27629369)
  • Lung function (FVC) ( 26635082)
  • Orofacial clefts ( 22863734)
  • Periodontitis (Mean PAL) ( 24024966)
  • Post-bronchodilator FEV1 x air pollution (NO2) interaction in childhood asthma ( 31028280)
  • Systemic lupus erythematosus ( 28714469)
  • Systolic blood pressure ( 27841878)
  • Tea consumption ( 31046077)
  • Thrombosis ( 26908601)
  • Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes 8 interacting genes: AXL DLL1 EFNA1 EFNA2 EPHA3 SH3D19 TCF12 TGFA 29 interacting genes: ABL1 ADAM10 CDKN2A CRK CTDSP2 DUSP18 DUSP21 EFNA1 EFNA2 EFNA3 EFNA4 EFNA5 EFNB1 EFNB2 ERBB2 FBXO7 FYN ILKAP MTMR11 PIM1 RBM18 RUFY1 RUFY2 SRC SRPK1 STAT3 STYX TP53 TPTE
Entrez ID 102 2042
HPRD ID 03723 01555
Ensembl ID ENSG00000137845 ENSG00000044524
Uniprot IDs A0A024R5U5 O14672 A0A140VJJ0 C9JXA2 P29320 Q6P4R6
PDB IDs 1M1I 6BDZ 6BE6 2GSF 2QO2 2QO7 2QO9 2QOB 2QOC 2QOD 2QOF 2QOI 2QOK 2QOL 2QON 2QOO 2QOQ 3DZQ 3FXX 3FY2 4G2F 4GK2 4GK3 4GK4 4L0P 4P4C 4P5Q 4P5Z 4TWN 4TWO 6IN0
Enriched GO Terms of Interacting Partners?
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