ABI2 and KRT19

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ABI2	KRT19
Description		abl interactor 2	keratin 19
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Cytoskeleton Adherens Junction Lamellipodium SCAR Complex Filopodium Tip Dendritic Spine	Cytosol Intermediate Filament Plasma Membrane Dystrophin-associated Glycoprotein Complex Apicolateral Plasma Membrane Z Disc Sarcolemma Costamere Extracellular Exosome Cell Periphery Terminal Web
	Molecular Function	DNA Binding Protein Binding Cytoskeletal Adaptor Activity SH3 Domain Binding Kinase Binding Ubiquitin Protein Ligase Binding Rac GTPase Binding Proline-rich Region Binding	Structural Constituent Of Cytoskeleton Protein Binding Structural Constituent Of Muscle Protein-containing Complex Binding
	Biological Process	Cytoskeleton Organization Actin Polymerization Or Depolymerization Viral Process Cell Migration Rac Protein Signal Transduction Peptidyl-tyrosine Phosphorylation Regulation Of Dendritic Spine Morphogenesis Lens Fiber Cell Morphogenesis Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation	Notch Signaling Pathway Viral Process Keratinization Response To Estrogen Sarcomere Organization Cell Differentiation Involved In Embryonic Placenta Development Cornification
Pathways		Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation VEGFA-VEGFR2 Pathway RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis	Keratinization Formation of the cornified envelope
Drugs
Diseases
GWAS		Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Butyrylcholinesterase levels ( 21862451) Diverticular disease ( 30177863) Subclinical atherosclerosis traits (other) ( 17903303) Trunk fat mass ( 28552196) Urinary albumin-to-creatinine ratio ( 31511532)
Interacting Genes		61 interacting genes: ABL1 ADAM19 ARHGAP32 ARMC7 BLOC1S6 CCDC102B CCHCR1 CDK6 CRX DTNB EFS EGLN3 EIF3H ENAH GCC1 HGS HNRNPK HOMER3 IFT20 IHO1 KHDRBS1 KIAA1217 KIFC3 KRT13 KRT15 KRT19 KRT20 KRT31 KRT33B LMO2 MCM7 MRFAP1L1 MRPL44 NCK1 NCK2 NUP62 PCM1 PIN1 PPIF PRAM1 PRKAA1 PRKAA2 PRR16 SDCBP SH3KBP1 SMARCB1 SNAP23 STAM2 TFIP11 TLE5 TRAF3IP1 TRIM32 TRIP6 VARS2 VASP VCL VPS37C WASF2 WASHC3 WIPF1 ZNF688	41 interacting genes: ABI2 AMOTL2 APC C1orf109 CARD9 CCDC146 CEP57L1 COPS4 DEPP1 DGCR6L DMD EIF4E2 EIF4ENIF1 ESR1 EXOC8 FAM107A FAM124B FANCG GFAP HAUS1 HGS IKZF3 KDM1A KIFC3 KRT15 KRT2 KRT6B PCM1 PLEKHA5 PNN POLR1C PPP1R18 SFI1 SMARCB1 TBC1D7 TFPT TUBG1 UBE2I UCHL5 USHBP1 ZNF638
Entrez ID		10152	3880
HPRD ID		07338	01007
Ensembl ID		ENSG00000138443	ENSG00000171345
Uniprot IDs		A0A0C4DG21 B7Z836 E9PEZ7 F8WAL6 Q9NYB9	P08727
PDB IDs		2ED0 3P8C 4N78
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?