TRIM10 and PRKAB2

Number of citations of the paper that reports this interaction (PubMedID 24722188)
51

Data Source:
BioGRID (two hybrid)

		TRIM10	PRKAB2
Description		tripartite motif containing 10	protein kinase AMP-activated non-catalytic subunit beta 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Nucleus Nucleoplasm Cytoplasm Cytosol Nucleotide-activated Protein Kinase Complex
	Molecular Function	Molecular_function Protein Binding Zinc Ion Binding	AMP-activated Protein Kinase Activity Protein Binding Protein Kinase Binding Identical Protein Binding
	Biological Process	Biological_process Erythrocyte Differentiation Innate Immune Response Negative Regulation Of Viral Entry Into Host Cell	Protein Phosphorylation Fatty Acid Biosynthetic Process Carnitine Shuttle Cell Cycle Arrest Signal Transduction Macroautophagy Regulation Of Macroautophagy Regulation Of Fatty Acid Biosynthetic Process Regulation Of Catalytic Activity Positive Regulation Of Cold-induced Thermogenesis Regulation Of Signal Transduction By P53 Class Mediator
Pathways		Interferon gamma signaling	Translocation of SLC2A4 (GLUT4) to the plasma membrane Macroautophagy AMPK inhibits chREBP transcriptional activation activity AMPK inhibits chREBP transcriptional activation activity Carnitine metabolism Activation of PPARGC1A (PGC-1alpha) by phosphorylation Energy dependent regulation of mTOR by LKB1-AMPK TP53 Regulates Metabolic Genes Regulation of TP53 Activity through Phosphorylation Lipophagy Activation of AMPK downstream of NMDARs
Drugs			Adenosine monophosphate Acetylsalicylic acid
Diseases
GWAS		Anger ( 24489884) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252) HIV-1 control ( 20041166) Immature fraction of reticulocytes ( 27863252) Mean corpuscular hemoglobin concentration ( 27863252) Neuroticism ( 29255261) Red cell distribution width ( 27863252) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252)
Interacting Genes		8 interacting genes: PRKAB2 PSMA1 TTC23 UBE2D1 UBE2D2 UBE2D3 UBE2D4 ZNF148	74 interacting genes: ADAMTSL4 BANP BEND5 BLZF1 CALCOCO2 CASP6 CCDC33 CDX4 CREB3L1 CRX CSNK2B DAO DDIT4L DICER1 DST EPM2A FDX1 FLNC GATA1 GATAD2B GET4 GOLGA2 GRN IHO1 IKZF1 IKZF3 KCTD5 KLF15 KRT40 KRTAP1-3 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP4-12 KRTAP4-2 KRTAP5-9 KRTAP9-2 KRTAP9-4 LZTS2 MAGED1 MDFI MEOX2 NEBL PIAS2 PNMA1 PRDM14 PRKAA1 PRKAG1 PRKAG2 PSME3 PYGM RACK1 RBPMS REL RHEBL1 RIMBP3 SPRY2 SSX2IP STX11 STX19 TADA2A TASOR2 TCF4 TLE5 TP53 TP53BP2 TRAF1 TRAF2 TRIM10 UBXN11 YY1AP1 ZBTB32
Entrez ID		10107	5565
HPRD ID		05752	04117
Ensembl ID		ENSG00000204613	ENSG00000131791
Uniprot IDs		A0A1U9X8M5 Q9UDY6	O43741
PDB IDs			2F15 2V8Q 2V92 2V9J 2Y8L 2Y8Q 2YA3 4CFH 4EAI 4EAJ 4RER 4REW 6B2E
Enriched GO Terms of Interacting Partners?
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