NAT2 and ERBB2

  • Number of citations of the paper that reports this interaction (PubMedID 25640309)
  • 5
  • Data Source:
  • BioGRID (two hybrid)

NAT2

ERBB2

Description N-acetyltransferase 2 erb-b2 receptor tyrosine kinase 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Bladder cancer ( 24163127 20972438)
  • Blood metabolite levels ( 24816252)
  • Blood metabolite ratios ( 24816252)
  • Cholesterol, total ( 24097068 20686565)
  • Coronary artery disease ( 29212778)
  • Insulin resistance/response ( 25798622)
  • Iron status biomarkers (transferrin levels) ( 25352340)
  • LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Liver injury in anti-tuberculosis drug treatment ( 31109976)
  • Medication use (calcium channel blockers) ( 31015401)
  • Medication use (HMG CoA reductase inhibitors) ( 31015401)
  • Metabolic syndrome ( 31589552)
  • Metabolic traits ( 21886157)
  • Metabolite levels ( 23823483)
  • Night sleep phenotypes ( 27126917)
  • Paclitaxel-induced neuropathy ( 23776197)
  • Total cholesterol levels ( 28334899)
  • Triglyceride levels ( 28334899 29403010 30698716)
  • Triglyceride levels in current drinkers ( 30698716)
  • Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Triglyceride levels x long total sleep time interaction (2df test) ( 31719535)
  • Triglyceride levels x short total sleep time interaction (2df test) ( 31719535)
  • Triglycerides ( 24097068 20686565)
  • Urinary metabolite levels in chronic kidney disease ( 31959995)
  • Urinary metabolite modules (eigenmetabolites) in chronic kidney disease ( 31959995)
  • Urinary metabolites ( 26352407 21572414)
  • Urinary metabolites (H-NMR features) ( 24586186)
Interacting Genes 16 interacting genes: APC APP AURKA BAG4 CDKN2A CDKN2C ERBB2 FZR1 HMMR IGF1R NAA10 NBN PALB2 PPM1D STK11 WT1 208 interacting genes: ABCB5 ABL1 ABL2 ACP3 ADGRB1 AKT1 ALK ANKS1A ANKS1B ANXA6 APBB1 APBB3 ARNT ATP6AP1 AURKA BCAR3 BECN1 BLK BLNK BMX BTC CALM1 CAV1 CBLC CCND2 CD44 CD82 CDK4 CDK6 CDKN2B CDKN2C CHN1 CISH CLCN6 CLNK CRK CRKL CTNNB1 CXCL8 CYP17A1 DAB1 DDR1 DLG4 DOK1 DOK4 DOK6 DUSP14 DUSP18 DUSP19 EGF EGFR EPHA1 EPHA2 EPHA3 EPHA4 EPHA5 EPHB1 EPHB2 EPHB3 EPHB6 ERBB3 ERBB4 ERBIN ERRFI1 ESR1 FBXO7 FER FGFR1 FGFR2 FGFR3 FGFR4 FGR FLT3 FLT4 FZR1 GAB1 GLCE GLIS2 GMPR2 GRB2 GRB7 GRM1 HDAC6 HDLBP HGF HLA-A HRAS HSP90AA1 HSP90B1 IARS1 IGF1R IL13RA2 IL6ST ILKAP INSR INSRR IRS1 IRS4 ITGA5 ITGB4 ITK JAK1 JAK2 JUP KDELR2 KLK5 LATS2 LYPD3 MAP2K3 MAP2K5 MAPK8IP1 MAPK8IP2 MATK MERTK MET MST1R MTCH1 MUC1 MUC4 MUCL1 MYC NAT2 NCK2 NF2 NRG1 NTRK1 NTRK2 NTRK3 PAK1 PDGFRA PDGFRB PHF23 PICK1 PIK3C2A PIK3C2B PIK3R1 PIK3R2 PIK3R3 PLCG1 POLD2 PPM1A PPM1F PRDM14 PSAP PSMC3IP PSMD3 PTK2 PTK2B PTK7 PTPN11 PTPN18 PTPN6 PTPRR PTPRT PTPRU RAF1 RASA1 RASSF1 RET RHOBTB2 RIN1 RIN2 ROR2 SERPINA3 SH2B2 SH2B3 SH2D1B SH2D2A SH2D3A SH2D5 SH3BGRL3 SH3BP2 SHC1 SHC2 SHC3 SLA SLA2 SOCS1 SOS1 SRC SRPK1 STAT3 STK11 STK24 STUB1 STYK1 STYX SUPT6H SYK TCEAL2 TEC TGFA THRSP TLN1 TNS2 TNS3 TOB1 TP53 TTC9B TTYH2 TXK TYRO3 UBB USP2 UTP18 VAV1 VAV2 VAV3
Entrez ID 10 2064
HPRD ID 02000 01281
Ensembl ID ENSG00000156006 ENSG00000141736
Uniprot IDs A4Z6T7 P11245 F5H1T4 J3QLU9 P04626 X5DNK3
PDB IDs 2PFR 1MFG 1MFL 1MW4 1N8Z 1OVC 1QR1 1S78 2A91 2JWA 2KS1 2L4K 2N2A 3BE1 3H3B 3MZW 3N85 3PP0 3RCD 3WLW 3WSQ 4GFU 4HRL 4HRM 4HRN 5K33 5KWG 5MY6 5O4G 5OB4 5TQS 6ATT 6BGT 6J71 6OGE
Enriched GO Terms of Interacting Partners?
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