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WASF1

Description WASP family member 1
Image
GO Annotations Cellular Component
  • Mitochondrial Outer Membrane
  • Cytoskeleton
  • Focal Adhesion
  • Actin Cytoskeleton
  • Lamellipodium
  • SCAR Complex
  • Dendrite Cytoplasm
  • Protein-containing Complex
  • Postsynapse
Molecular Function
  • Actin Binding
  • Protein Binding
  • Rac GTPase Binding
  • Protein Kinase A Binding
Biological Process
  • Receptor-mediated Endocytosis
  • Rac Protein Signal Transduction
  • Actin Filament Polymerization
  • Positive Regulation Of Neurotrophin TRK Receptor Signaling Pathway
  • Protein-containing Complex Assembly
  • Lamellipodium Morphogenesis
  • Dendrite Extension
  • Modification Of Postsynaptic Actin Cytoskeleton
  • Dendritic Transport Of Mitochondrion
  • Cellular Response To Brain-derived Neurotrophic Factor Stimulus
  • Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Pathways
  • Regulation of actin dynamics for phagocytic cup formation
  • Regulation of actin dynamics for phagocytic cup formation
  • VEGFA-VEGFR2 Pathway
  • RHO GTPases Activate WASPs and WAVEs
  • RHO GTPases Activate WASPs and WAVEs
  • FCGR3A-mediated phagocytosis
  • FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS
Interacting Genes 31 interacting genes: ABI1 ABL1 ACTB ACTG1 ACTR2 ACTR3 BAD BAIAP2 BRK1 CDC42 CDK5 CRK CXCL8 CYFIP2 DNMBP FYN GNAI1 GRB2 IFT20 IL12A MAPKAPK2 NCK1 NCKAP1 NYAP2 PFN1 PRKAR2A PSTPIP1 RAC1 SORBS2 SRGAP3 TRIP10
Entrez ID 8936
HPRD ID 05434
Ensembl ID ENSG00000112290
Uniprot IDs Q92558
PDB IDs 3P8C 4N78
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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