ALG8

Description		ALG8 alpha-1,3-glucosyltransferase
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Alpha-1,3-mannosyltransferase Activity Dolichyl-phosphate-glucose-glycolipid Alpha-glucosyltransferase Activity Protein Binding Dolichyl Pyrophosphate Man9GlcNAc2 Alpha-1,3-glucosyltransferase Activity Dolichyl Pyrophosphate Glc1Man9GlcNAc2 Alpha-1,3-glucosyltransferase Activity
	Biological Process	Protein N-linked Glycosylation Dolichol-linked Oligosaccharide Biosynthetic Process Oligosaccharide-lipid Intermediate Biosynthetic Process Protein N-linked Glycosylation Via Asparagine Mannosylation
Pathways		Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein Defective ALG8 causes ALG8-CDG (CDG-1h)
Drugs
Diseases		Congenital disorders of glycosylation (CDG) type I
GWAS		Depression in smokers ( 30219690) Tourette syndrome ( 30818990)
Interacting Genes		8 interacting genes: CREB3 IQGAP2 LMNA NAE1 NARS2 RPS6KA5 RSF1 TMEM126B
Entrez ID		79053
HPRD ID		10480
Ensembl ID		ENSG00000159063
Uniprot IDs		A0A024R5K5 Q9BVK2
PDB IDs
Enriched GO Terms of Interacting Partners?
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