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UBE2A

Description ubiquitin conjugating enzyme E2 A
Image
GO Annotations Cellular Component
  • Chromatin
  • Nuclear Chromatin
  • XY Body
  • Nucleoplasm
  • Cytosol
  • HULC Complex
Molecular Function
  • Ubiquitin-protein Transferase Activity
  • Protein Binding
  • ATP Binding
  • Ubiquitin Protein Ligase Binding
  • Ubiquitin Conjugating Enzyme Activity
Biological Process
  • Protein Polyubiquitination
  • Blastocyst Hatching
  • DNA Repair
  • Postreplication Repair
  • Ubiquitin-dependent Protein Catabolic Process
  • Positive Regulation Of Cell Proliferation
  • Response To UV
  • Protein Ubiquitination
  • Histone Ubiquitination
  • Histone H2A Ubiquitination
  • Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
  • Protein Autoubiquitination
  • Maternal Process Involved In Female Pregnancy
  • Protein K48-linked Ubiquitination
  • Protein K11-linked Ubiquitination
Pathways
  • Synthesis of active ubiquitin: roles of E1 and E2 enzymes
  • E3 ubiquitin ligases ubiquitinate target proteins
  • Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
  • Brain connectivity ( 23471985)
Interacting Genes 26 interacting genes: CBX5 CDK1 CDK2 CDK9 CDKN2A CRMP1 EEF1D H2BC21 HLTF KCMF1 MDM2 PCNA PRKN RAD18 RC3H1 RNF20 RNF4 RNF40 SDCBP TP53 TRIM27 UBA1 UBR1 UBR3 UBR5 ZMYM2
Entrez ID 7319
HPRD ID 02422
Ensembl ID ENSG00000077721
Uniprot IDs A0A0D9SG71 P49459
PDB IDs 6CYO 6CYR
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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