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CCL8

Description C-C motif chemokine ligand 8
Image
GO Annotations Cellular Component
  • Extracellular Space
  • Cell
Molecular Function
  • Protein Kinase Activity
  • Protein Binding
  • Chemokine Activity
  • Heparin Binding
  • Phospholipase Activator Activity
  • CCR Chemokine Receptor Binding
Biological Process
  • Monocyte Chemotaxis
  • Positive Regulation Of Leukocyte Migration
  • Protein Phosphorylation
  • Calcium Ion Transport
  • Cellular Calcium Ion Homeostasis
  • Exocytosis
  • Chemotaxis
  • Inflammatory Response
  • Signal Transduction
  • G Protein-coupled Receptor Signaling Pathway
  • Cell-cell Signaling
  • Response To Virus
  • Neutrophil Chemotaxis
  • Positive Regulation Of GTPase Activity
  • Negative Regulation By Host Of Viral Genome Replication
  • Eosinophil Chemotaxis
  • Lymphocyte Chemotaxis
  • Chemokine-mediated Signaling Pathway
  • Positive Regulation Of ERK1 And ERK2 Cascade
  • Negative Regulation Of Leukocyte Proliferation
  • Cellular Response To Interferon-gamma
  • Cellular Response To Interleukin-1
  • Cellular Response To Tumor Necrosis Factor
Pathways
Drugs
  • Pidolic Acid
Diseases
GWAS
  • Blood protein levels ( 30072576 29875488 28240269)
  • Crohn's disease ( 22412388)
Interacting Genes 9 interacting genes: ACKR1 ACKR2 ACKR4 CCR1 CCR3 CCR5 MMP3 SDF2 VCAN
Entrez ID 6355
HPRD ID 03791
Ensembl ID ENSG00000108700
Uniprot IDs P80075
PDB IDs 1ESR
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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