KLHL3

Description		kelch like family member 3
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GO Annotations	Cellular Component	Cytosol Cytoskeleton Cul3-RING Ubiquitin Ligase Complex
	Molecular Function	Actin Binding Structural Molecule Activity Protein Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Post-translational Protein Modification Ion Homeostasis Selective Autophagy Renal Sodium Ion Absorption Protein K48-linked Ubiquitination Distal Tubule Morphogenesis
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Bronchopulmonary dysplasia ( 23897914) Heart failure ( 31919418) Severe malaria ( 29381699) Severe malaria (adjusted for sickle cell variant rs334) ( 29381699)
Interacting Genes		16 interacting genes: AKT1 CFAP206 CUL3 GNAI1 GNAO1 KEAP1 KLHL12 MORF4L2 OPRD1 PPP3CA PRKACA SYNCRIP SYT2 WNK1 WNK3 WNK4
Entrez ID		26249
HPRD ID		09011
Ensembl ID		ENSG00000146021
Uniprot IDs		Q9UH77
PDB IDs		4CH9 4HXI 5NKP
Enriched GO Terms of Interacting Partners?
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