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SH2B2

Description SH2B adaptor protein 2
Image
GO Annotations Cellular Component
  • Cytoplasm
  • Cytosol
  • Plasma Membrane
Molecular Function
  • Transmembrane Receptor Protein Tyrosine Kinase Adaptor Activity
  • SH3/SH2 Adaptor Activity
  • Protein Binding
Biological Process
  • Signal Transduction
  • Blood Coagulation
  • Insulin Receptor Signaling Pathway
  • Positive Regulation Of Signal Transduction
  • Intracellular Signal Transduction
  • Antigen Receptor-mediated Signaling Pathway
Pathways
  • Regulation of KIT signaling
  • Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS
  • Type 2 diabetes ( 31049640)
Interacting Genes 22 interacting genes: AKT1 ASB6 BTK CBL EPOR ERBB2 FYN GRB2 INSR JAK1 JAK2 JAK3 KIT LYN MTDH NTRK1 NTRK2 PDLIM7 SH2B1 SHC1 SORBS1 SYK
Entrez ID 10603
HPRD ID 16097
Ensembl ID ENSG00000160999
Uniprot IDs O14492
PDB IDs 1Q2H
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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