TELO2 and IFT140

Data Source:
BioGRID (affinity chromatography technology)

		TELO2	IFT140
Description		telomere maintenance 2	intraflagellar transport 140
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Membrane Nuclear Body TORC1 Complex TORC2 Complex Nuclear Periphery ASTRA Complex	Photoreceptor Outer Segment Centrosome Centriole Cilium Axoneme Intraciliary Transport Particle A Photoreceptor Connecting Cilium Ciliary Basal Body Ciliary Tip
	Molecular Function	Protein Binding Protein Kinase Binding Telomeric DNA Binding Protein-containing Complex Binding Hsp90 Protein Binding Molecular Adaptor Activity	Molecular_function Protein Binding
	Biological Process	Telomere Maintenance Via Telomerase Regulation Of TOR Signaling Protein Stabilization Positive Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of TORC1 Signaling Positive Regulation Of TORC2 Signaling	Determination Of Left/right Symmetry Heart Development Regulation Of Smoothened Signaling Pathway Neural Tube Patterning Embryonic Camera-type Eye Development Intraciliary Retrograde Transport Intraciliary Transport Involved In Cilium Assembly Photoreceptor Cell Outer Segment Organization Intraciliary Transport Embryonic Digit Morphogenesis Embryonic Cranial Skeleton Morphogenesis Cilium Assembly Protein Localization To Cilium Regulation Of Cilium Assembly Non-motile Cilium Assembly Embryonic Brain Development
Pathways			Hedgehog 'off' state Intraflagellar transport
Drugs
Diseases
GWAS		Rheumatoid arthritis ( 30891314)	Coronary artery disease ( 29212778 33020668) Epilepsy and lamotrigine-induced maculopapular eruptions ( 26220383)
Interacting Genes		5 interacting genes: ATM CACNA1A KAT5 KRT15 MTOR	5 interacting genes: CELSR3 CRK NEK2 PFDN1 RANBP2
Entrez ID		9894	9742
HPRD ID		10016	11093
Ensembl ID		ENSG00000100726	ENSG00000187535
Uniprot IDs		B4DXS2 Q9Y4R8	Q96RY7
PDB IDs		4PSI
Enriched GO Terms of Interacting Partners?
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