TOMM70 and NIT2

Data Source:
BioGRID (biochemical)

		TOMM70	NIT2
Description		translocase of outer mitochondrial membrane 70	nitrilase family member 2
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Mitochondrial Outer Membrane Translocase Complex Membrane Integral Component Of Membrane Extracellular Exosome	Extracellular Region Centrosome Cytosol Specific Granule Lumen Extracellular Exosome Tertiary Granule Lumen
	Molecular Function	Protein Binding Protein Transmembrane Transporter Activity Mitochondrion Targeting Sequence Binding	Omega-amidase Activity
	Biological Process	Activation Of Innate Immune Response Positive Regulation Of Defense Response To Virus By Host Protein Targeting To Mitochondrion Macroautophagy Protein Import Into Mitochondrial Matrix Positive Regulation Of Interferon-beta Production Regulation Of Apoptotic Process Protein Insertion Into Mitochondrial Inner Membrane Cellular Response To Virus	Oxaloacetate Metabolic Process Asparagine Metabolic Process Glutamine Metabolic Process Neutrophil Degranulation
Pathways		Mitochondrial protein import PINK1-PRKN Mediated Mitophagy Ub-specific processing proteases	Neutrophil degranulation
Drugs
Diseases
GWAS			Age-related cognitive decline (language) (slope of z-scores) ( 30954325) Refractive error ( 32231278)
Interacting Genes		7 interacting genes: HSP90AA1 HSPA1A HSPA1B HSPB1 IRF3 PRKN SNAPIN
Entrez ID		9868	56954
HPRD ID		16194	17634
Ensembl ID		ENSG00000154174	ENSG00000114021
Uniprot IDs		O94826	Q9NQR4 V9HW91
PDB IDs		7KDT
Enriched GO Terms of Interacting Partners?
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