CDC42BPB and AMN

Data Source:
BioGRID (affinity chromatography technology)

		CDC42BPB	AMN
Description		CDC42 binding protein kinase beta	amnion associated transmembrane protein
Image
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Plasma Membrane Cell-cell Junction Lamellipodium Cell Leading Edge Actomyosin Extracellular Exosome	Extracellular Space Plasma Membrane Clathrin-coated Pit Endosome Membrane Integral Component Of Membrane Apical Plasma Membrane Endocytic Vesicle Brush Border Membrane Protein-containing Complex Extracellular Exosome
	Molecular Function	Magnesium Ion Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity ATP Binding Protein-containing Complex Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity	Signaling Receptor Binding Protein Binding
	Biological Process	Protein Phosphorylation Cytoskeleton Organization Establishment Or Maintenance Of Cell Polarity Signal Transduction Cell Migration Peptidyl-threonine Phosphorylation Actomyosin Structure Organization Actin Cytoskeleton Reorganization Intracellular Signal Transduction	Receptor-mediated Endocytosis Multicellular Organism Development Excretion Protein Localization Cobalamin Metabolic Process Cobalamin Transport High-density Lipoprotein Particle Clearance Golgi To Plasma Membrane Protein Transport
Pathways			Cobalamin (Cbl, vitamin B12) transport and metabolism Defective AMN causes hereditary megaloblastic anemia 1 Defective CUBN causes hereditary megaloblastic anemia 1 HDL clearance
Drugs			Hydroxocobalamin
Diseases
GWAS		Body mass index ( 26426971) Large B-cell lymphoma ( 21471979) Mean platelet volume ( 32888494) Refractive error ( 32231278)	Body mass index ( 26426971)
Interacting Genes		7 interacting genes: CDC42 CDC42BPA MAP2K5 PPM1A PPP2CA PYGM RIPK1	1 interacting genes: STAMBP
Entrez ID		9578	81693
HPRD ID		08516	09314
Ensembl ID		ENSG00000198752	ENSG00000166126
Uniprot IDs		A0A024R6N2 Q86XZ8 Q9Y5S2	B3KP64 Q9BXJ7
PDB IDs		3QFV 3TKU 4UAK 4UAL 5OTE 5OTF	6GJE
Enriched GO Terms of Interacting Partners?
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