BAG5 and ANXA3

Data Source:
BioGRID (affinity chromatography technology)

		BAG5	ANXA3
Description		BAG cochaperone 5	annexin A3
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Cytosol Membrane Inclusion Body Perinuclear Region Of Cytoplasm	Cytoplasm Plasma Membrane Membrane Axon Dendrite Phagocytic Vesicle Membrane Specific Granule Neuronal Cell Body Extracellular Exosome
	Molecular Function	Adenyl-nucleotide Exchange Factor Activity Protein Binding Protein Kinase Binding Heat Shock Protein Binding Ubiquitin Protein Ligase Binding Chaperone Binding	Calcium Ion Binding Calcium-dependent Phospholipid Binding Phospholipase A2 Inhibitor Activity Calcium-dependent Protein Binding
	Biological Process	Protein Folding Golgi Organization Negative Regulation Of Neuron Projection Development Negative Regulation Of Protein Ubiquitination Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Stabilization Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Protein Refolding Neuron Death Regulation Of Inclusion Body Assembly Regulation Of Cellular Response To Heat Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway	Phagocytosis Positive Regulation Of Endothelial Cell Migration Hippocampus Development Animal Organ Regeneration Defense Response To Bacterium Negative Regulation Of Catalytic Activity Neutrophil Degranulation Positive Regulation Of Angiogenesis Positive Regulation Of DNA Metabolic Process Positive Regulation Of DNA-binding Transcription Factor Activity Response To Glucocorticoid Response To Growth Factor
Pathways		Regulation of HSF1-mediated heat shock response
Drugs			Fluocinolone acetonide Ethanolamine Difluocortolone
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545) Broad depression or schizophrenia ( 30626913) Depression ( 29700475) Schizophrenia ( 25056061)	Amyotrophic lateral sclerosis (sporadic) ( 24529757) Metabolite levels ( 23823483) Non-albumin protein levels ( 22558069) Refractive error ( 32231278) Rheumatoid arthritis ( 30423114 22446963)
Interacting Genes		19 interacting genes: BANP CDCA7L CIRBP DES EFEMP1 FAM118B GOLGA6A HSPA4 KASH5 KRTAP5-4 LRRK1 MAD1L1 PINK1 PRKN SNCA STUB1 THAP1 TP53 TRIM27	6 interacting genes: EMG1 IGSF21 REG3A TP53 UBR1 UNC119
Entrez ID		9529	306
HPRD ID		04862	00111
Ensembl ID		ENSG00000166170	ENSG00000138772
Uniprot IDs		A0A024R6M6 Q9UL15	P12429
PDB IDs		2D9D 3A8Y	1AII 1AXN
Enriched GO Terms of Interacting Partners?
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