CD27 and CREBL2

Data Source:
BioGRID (affinity chromatography technology)

		CD27	CREBL2
Description		CD27 molecule	cAMP responsive element binding protein like 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane	Chromatin Nucleus
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding
	Biological Process	Cell Surface Receptor Signaling Pathway Immunoglobulin Mediated Immune Response Tumor Necrosis Factor-mediated Signaling Pathway Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Response To Ethanol Positive Regulation Of B Cell Differentiation Positive Regulation Of T Cell Differentiation Positive Regulation Of JNK Cascade Negative Regulation Of T Cell Apoptotic Process Extrinsic Apoptotic Signaling Pathway Positive Regulation Of NIK/NF-kappaB Signaling	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Cell Cycle Signal Transduction Cell Differentiation Positive Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Fat Cell Differentiation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Glucose Import Positive Regulation Of Lipid Biosynthetic Process Protein Stabilization
Pathways		TNFs bind their physiological receptors
Drugs
Diseases
GWAS		Crohn's disease ( 26192919)	Height ( 31562340) Midgestational circulating levels of PBDEs (fetal genetic effect) ( 28235828) Response to fenofibrate (HDL cholesterol levels) ( 27002377) Systemic lupus erythematosus ( 23273568)
Interacting Genes		8 interacting genes: ACTN2 CD70 CIB1 SIVA1 TRAF2 TRAF3 TRAF5 UHRF2	5 interacting genes: CREBRF DDIT3 DNMT3L PKNOX2 UBE2I
Entrez ID		939	1389
HPRD ID		01723	07541
Ensembl ID		ENSG00000139193	ENSG00000111269
Uniprot IDs		P26842	O60519
PDB IDs		5TL5 5TLJ 5TLK
Enriched GO Terms of Interacting Partners?
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