CD83 and GMPR

Data Source:
BioGRID (biochemical)

		CD83	GMPR
Description		CD83 molecule	guanosine monophosphate reductase
Image
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane	Cytosol GMP Reductase Complex
	Molecular Function	Protein Binding	GMP Reductase Activity Metal Ion Binding
	Biological Process	Defense Response Humoral Immune Response Signal Transduction Response To Organic Cyclic Compound Negative Regulation Of Interleukin-4 Production Positive Regulation Of Interleukin-10 Production Positive Regulation Of Interleukin-2 Production Positive Regulation Of CD4-positive, Alpha-beta T Cell Differentiation	Purine Nucleobase Metabolic Process Purine Nucleotide Metabolic Process Response To Cold Purine-containing Compound Salvage
Pathways			Purine salvage
Drugs			Guanosine-5'-Monophosphate
Diseases
GWAS		Breast cancer and/or colorectal cancer ( 29698419) California verbal learning test score ( 31596458) Chronotype ( 30696823) Obesity-related traits ( 23251661) Rheumatoid arthritis ( 30423114 22446963 24390342)	Blood metabolite levels ( 24816252) Gambling ( 22780124) General cognitive ability ( 29844566) Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494) LDL cholesterol ( 20864672) Major depressive disorder ( 23377640) Mean corpuscular hemoglobin ( 29403010 32888494 27863252) Mean corpuscular hemoglobin concentration ( 29403010 32888494 27863252) Mean corpuscular volume ( 29403010 32888494 27863252) Mean spheric corpuscular volume ( 32888494) QT interval ( 24952745 29874175) Red blood cell count ( 32888494) Red cell distribution width ( 32888494) Response to statins (LDL cholesterol change) ( 22331829) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252)
Interacting Genes		2 interacting genes: EIF4E FATE1
Entrez ID		9308	2766
HPRD ID		05170	00754
Ensembl ID		ENSG00000112149	ENSG00000137198
Uniprot IDs		A0A087WX61 Q01151	P36959
PDB IDs		5MIX 5MJ0 5MJ1 5MJ2	2BLE 2BWG
Enriched GO Terms of Interacting Partners?
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