CD83 and SACS

Data Source:
BioGRID (affinity chromatography technology)

		CD83	SACS
Description		CD83 molecule	sacsin molecular chaperone
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane	Nucleus Cytoplasm Mitochondrion Axon Dendrite Cell Body Fiber
	Molecular Function	Protein Binding	Hsp70 Protein Binding Chaperone Binding Proteasome Binding
	Biological Process	Defense Response Humoral Immune Response Signal Transduction Response To Organic Cyclic Compound Negative Regulation Of Interleukin-4 Production Positive Regulation Of Interleukin-10 Production Positive Regulation Of Interleukin-2 Production Positive Regulation Of CD4-positive, Alpha-beta T Cell Differentiation	Protein Folding Negative Regulation Of Inclusion Body Assembly
Pathways
Drugs
Diseases
GWAS		Breast cancer and/or colorectal cancer ( 29698419) California verbal learning test score ( 31596458) Chronotype ( 30696823) Obesity-related traits ( 23251661) Rheumatoid arthritis ( 30423114 22446963 24390342)	Blood pressure (smoking interaction) ( 25189868) Hypothyroidism ( 22493691) Metabolite levels ( 23823483) Protein quantitative trait loci ( 18464913) Type 2 diabetes ( 23300278)
Interacting Genes		2 interacting genes: EIF4E FATE1	6 interacting genes: ACTN4 ADRB2 PICK1 POLR1H TSC22D4 UBE3A
Entrez ID		9308	26278
HPRD ID		05170	05135
Ensembl ID		ENSG00000112149	ENSG00000151835
Uniprot IDs		A0A087WX61 Q01151	Q9NZJ4
PDB IDs		5MIX 5MJ0 5MJ1 5MJ2	1IUR 3O10 5V44 5V45 5V46 5VSX 5VSZ
Enriched GO Terms of Interacting Partners?
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