COL23A1 and PTGES2

Data Source:
BioGRID (affinity chromatography technology)

		COL23A1	PTGES2
Description		collagen type XXIII alpha 1 chain	prostaglandin E synthase 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Collagen Trimer Extracellular Space Endoplasmic Reticulum Lumen Plasma Membrane Integral Component Of Membrane Extracellular Matrix Collagen-containing Extracellular Matrix	Golgi Membrane Extracellular Region Nucleus Mitochondrion Cytosol Integral Component Of Membrane Azurophil Granule Lumen Perinuclear Region Of Cytoplasm
	Molecular Function	Extracellular Matrix Structural Constituent Protein Binding Extracellular Matrix Structural Constituent Conferring Tensile Strength	DNA Binding Protein Binding Protein Disulfide Oxidoreductase Activity Lyase Activity Heme Binding Glutathione Binding Prostaglandin-E Synthase Activity
	Biological Process	Extracellular Matrix Organization	Lipid Metabolic Process Glutathione Metabolic Process Cyclooxygenase Pathway Neutrophil Degranulation Positive Regulation Of Transcription, DNA-templated
Pathways		Collagen degradation Collagen biosynthesis and modifying enzymes Integrin cell surface interactions Collagen chain trimerization	Synthesis of Prostaglandins (PG) and Thromboxanes (TX) Neutrophil degranulation
Drugs
Diseases			Penile cancer
GWAS		Blood protein levels ( 30072576) Bulimia nervosa ( 23568457) Cannabis dependence symptom count ( 27028160) Nose length ( 30174134) Obesity-related traits ( 23251661) Presence of antiphospholipid antibodies ( 27098658) Prostate cancer ( 29892016)	Body mass index ( 26426971)
Interacting Genes		3 interacting genes: EXOSC8 FURIN LSM8	5 interacting genes: ADRB2 C1orf189 CEBPB EXOSC10 PTGFR
Entrez ID		91522	80142
HPRD ID		16733	07458
Ensembl ID		ENSG00000050767	ENSG00000148334
Uniprot IDs		Q86Y22	A6NHH0 B3KPZ2 B4DWP1 Q9H7Z7
PDB IDs
Enriched GO Terms of Interacting Partners?
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