CDKL2 and G3BP2

Data Source:
BioGRID (affinity chromatography technology)

		CDKL2	G3BP2
Description		cyclin dependent kinase like 2	G3BP stress granule assembly factor 2
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Centrosome	Cytoplasm Cytosol Cytoplasmic Stress Granule Ribonucleoprotein Complex
	Molecular Function	Protein Kinase Activity Cyclin-dependent Protein Serine/threonine Kinase Activity ATP Binding	RNA Binding MRNA Binding Protein Binding Signaling Receptor Complex Adaptor Activity
	Biological Process	Protein Phosphorylation Signal Transduction Sex Differentiation Regulation Of Cell Cycle	Cytoplasmic Sequestering Of NF-kappaB Ras Protein Signal Transduction Viral Process Stress Granule Assembly Innate Immune Response MRNA Transport Protein Homooligomerization Positive Regulation Of Stress Granule Assembly
Pathways
Drugs		Fostamatinib
Diseases
GWAS		Subjective response to lithium treatment in bipolar disorder ( 26503763) Testicular germ cell tumor ( 28604728)	HDL cholesterol levels ( 32203549) Response to (pegylated) interferon in HBeAg-negative hepatitis B ( 30715261) Subjective response to lithium treatment in bipolar disorder ( 26503763) Testicular germ cell tumor ( 28604728)
Interacting Genes		2 interacting genes: APP CBL	60 interacting genes: MDM2 MIR1-1 MIR106A MIR106B MIR107 MIR10B MIR128-1 MIR128-2 MIR138-2 MIR140 MIR141 MIR145 MIR155 MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR19A MIR19B1 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29B1 MIR29C MIR31 MIR34A MIR34B MIR363 MIR429 MIR7-1 MIR7-2 MIR7-3 MIR92A1 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I NFKB1 NFKBIA PIN1 USP10 ZNF618
Entrez ID		8999	9908
HPRD ID		16021	06570
Ensembl ID		ENSG00000138769	ENSG00000138757
Uniprot IDs		A0A140VJG1 B4DH08 J3KNE8 Q92772	A0A024RDB2 A0A024RDE5 Q9UN86
PDB IDs		4AAA 4BBM	5DRV
Enriched GO Terms of Interacting Partners?
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