NKD2 and SHMT2

NKD2

SHMT2

Description NKD inhibitor of WNT signaling pathway 2 serine hydroxymethyltransferase 2
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Asthma ( 31619474)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Schizophrenia ( 25056061 29483656)
Interacting Genes 9 interacting genes: ANAPC11 CDKN1A FBXO7 FUS GRB2 LNX1 RCHY1 TGFA VDR 18 interacting genes: ABRAXAS2 APP ARL6IP1 BABAM1 BABAM2 BRCC3 CAB39 CLEC2D CMTM5 CREB3 CSNK2B DUX4 ESR1 FBXO7 KASH5 MAL2 NDRG1 PPARD
Entrez ID 85409 6472
HPRD ID 08483 00717
Ensembl ID ENSG00000145506 ENSG00000182199
Uniprot IDs Q969F2 A0A024RB99 B4DJQ3 B4DLV4 P34897 Q5BJF5 Q5HYG8 V9HW06
PDB IDs 4PVF 5V7I 5X3V 6DK3 6H3C 6QVG 6QVL 6R8F
Enriched GO Terms of Interacting Partners?
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