ST6GAL2 and AFF3

Data Source:
BioGRID (affinity chromatography technology, proximity labelling technology)

		ST6GAL2	AFF3
Description		ST6 beta-galactoside alpha-2,6-sialyltransferase 2	AF4/FMR2 family member 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Integral Component Of Membrane Golgi Cisterna Membrane	Nucleus Nucleoplasm Cytosol Nuclear Body Super Elongation Complex
	Molecular Function	Beta-galactoside Alpha-2,6-sialyltransferase Activity	Double-stranded DNA Binding DNA-binding Transcription Factor Activity
	Biological Process	Protein Glycosylation Oligosaccharide Metabolic Process Sialylation	Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Response To Tumor Necrosis Factor Embryonic Hindlimb Morphogenesis
Pathways		Sialic acid metabolism
Drugs
Diseases
GWAS		Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Serum immune biomarker levels ( 32066700)	Adult body size ( 32376654) Age at first birth ( 27798627) Albumin-globulin ratio ( 29403010) Apolipoprotein A1 levels ( 32203549) Arthritis (juvenile idiopathic) ( 33106285) Autoimmune traits (pleiotropy) ( 30572963) Cannabis dependence symptom count ( 27028160) Celiac disease ( 30572963) Celiac disease and Rheumatoid arthritis ( 26546613) Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) Extremely high intelligence ( 29520040) Gastroesophageal reflux disease ( 31527586) General cognitive ability ( 29844566) Hand grip strength ( 29691431) HDL cholesterol levels ( 32203549) Height ( 31217584) Household income ( 27818178) Household income (MTAG) ( 31844048) IgG levels ( 28628107) Immature fraction of reticulocytes ( 32888494) Intelligence ( 28530673) Intelligence (MTAG) ( 29326435) Intraocular pressure ( 29617998) Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular) ( 23603761) Kidney disease (end stage renal disease vs non-end stage renal disease) in type 1 diabetes ( 27647854) Mean corpuscular volume ( 32888494) Mean platelet volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Metabolite levels ( 23823483) Non-albumin protein levels ( 29403010) Number of children ever born ( 27798627) Plateletcrit ( 32888494 27863252) Red blood cell count ( 27863252) Refractive astigmatism ( 30306274) Regular attendance at a religious group ( 29970889) Rheumatoid arthritis ( 30423114 24782177 30572963 23143596 24390342 20453842) Rheumatoid arthritis (ACPA-positive) ( 23143596 24532676) Serum total protein level ( 29403010) Type 1 diabetes ( 25751624 17554260) Type 1 diabetes nephropathy ( 23028342)
Interacting Genes		16 interacting genes: AQP6 CD53 CREB3 FNDC9 GIPC3 GOLM1 GPX8 HSD17B13 PGRMC2 PSCA SLC26A1 SLC39A2 SLC7A1 TIMMDC1 TMEM14B TMEM237
Entrez ID		84620	3899
HPRD ID		12237	03272
Ensembl ID		ENSG00000144057	ENSG00000144218
Uniprot IDs		Q96JF0	P51826 Q8NAP7
PDB IDs
Enriched GO Terms of Interacting Partners?
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