DOC2A and TUFM

Data Source:
BioGRID (affinity chromatography technology)

		DOC2A	TUFM
Description		double C2 domain alpha	Tu translation elongation factor, mitochondrial
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Lysosome Cell Junction Neuron Projection Extrinsic Component Of Synaptic Vesicle Membrane	Mitochondrion Membrane Mitochondrial Nucleoid Synapse Extracellular Exosome
	Molecular Function	Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding	RNA Binding Translation Elongation Factor Activity GTPase Activity Protein Binding GTP Binding
	Biological Process	Chemical Synaptic Transmission Nervous System Development Synaptic Vesicle Exocytosis Regulation Of Calcium Ion-dependent Exocytosis Spontaneous Neurotransmitter Secretion	Translational Elongation Viral Process Response To Ethanol Mitochondrial Translational Elongation
Pathways			Mitochondrial translation elongation
Drugs			Zinc Guanosine-5'-Diphosphate Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases			Combined oxidative phosphorylation deficiency (COXPD)
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Height ( 28552196) Schizophrenia ( 28991256 25056061 29483656)	Alcohol consumption (drinks per week) ( 30643258) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body fat percentage ( 26833246) Body mass index ( 20935630) Brain morphology (MOSTest) ( 32665545) Crohn's disease ( 28067908) Educational attainment ( 25201988) Estimated glomerular filtration rate ( 31152163) Extremely high intelligence ( 29520040) Hip circumference adjusted for BMI ( 25673412) Inflammatory bowel disease ( 28067908) Intelligence ( 28530673) Lamb consumption ( 32066663)
Interacting Genes		5 interacting genes: DYNLT1 RAP1GDS1 STXBP1 UBASH3B UNC13B	18 interacting genes: ARL6IP1 ASPH ATP6V1A CMTM5 DGAT2L6 EXOSC6 FAM9B FUNDC1 HMBOX1 LINC01554 MTIF3 MYH9 PCAT1 PTEN RHBDD2 SYP TNFRSF10D ZDHHC15
Entrez ID		8448	7284
HPRD ID		05195	03861
Ensembl ID		ENSG00000149927	ENSG00000178952
Uniprot IDs		Q14183	A0A384ME17 P49411
PDB IDs		4MJJ
Enriched GO Terms of Interacting Partners?
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