UBXN8 and ADRB3

Data Source:
BioGRID (two hybrid)

		UBXN8	ADRB3
Description		UBX domain protein 8	adrenoceptor beta 3
Image		No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleoplasm Nucleolus Endoplasmic Reticulum Integral Component Of Endoplasmic Reticulum Membrane	Plasma Membrane Integral Component Of Plasma Membrane Receptor Complex
	Molecular Function	Protein Binding Protein-macromolecule Adaptor Activity	G Protein-coupled Receptor Activity Beta-adrenergic Receptor Activity Protein Binding Beta3-adrenergic Receptor Activity Protein Homodimerization Activity Epinephrine Binding Norepinephrine Binding
	Biological Process	Single Fertilization Ubiquitin-dependent ERAD Pathway	Norepinephrine-epinephrine-mediated Vasodilation Involved In Regulation Of Systemic Arterial Blood Pressure Desensitization Of G Protein-coupled Receptor Signaling Pathway By Arrestin Carbohydrate Metabolic Process Generation Of Precursor Metabolites And Energy Energy Reserve Metabolic Process Receptor-mediated Endocytosis G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Activation Of Adenylate Cyclase Activity Positive Regulation Of MAPK Cascade Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Positive Regulation Of Cold-induced Thermogenesis
Pathways			Adrenoceptors G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production
Drugs			Amphetamine Bethanidine Olanzapine Norepinephrine Nortriptyline Propranolol Paroxetine Trimipramine Cryptenamine Alprenolol Terbutaline Salmeterol Pindolol Formoterol Salbutamol Ergoloid mesylate Isoprenaline Arbutamine Amiodarone Fenoterol Ephedra sinica root Mephentermine Clenbuterol Oxprenolol Celiprolol Nebivolol Amibegron Solabegron Droxidopa Bufuralol Bopindolol Bupranolol Mirabegron Racepinephrine Dihydroergocornine DL-Methylephedrine Dihydroergocristine Vibegron
Diseases
GWAS
Interacting Genes		7 interacting genes: AQP6 GJA8 HSD17B13 MEOX2 PGRMC2 SPCS1 TMEM14B	3 interacting genes: ADRB2 GNAS SRC
Entrez ID		7993	155
HPRD ID		03692	00188
Ensembl ID		ENSG00000104691	ENSG00000188778
Uniprot IDs		B4DKK1 O00124	A8KAG8 P13945
PDB IDs			2CDW
Enriched GO Terms of Interacting Partners?
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